ID   GL8D1_RAT               Reviewed;         371 AA.
AC   Q6AYF6;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 1;
DE            EC=2.4.1.-;
GN   Name=Glt8d1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; BC079066; AAH79066.1; -; mRNA.
DR   RefSeq; NP_001007684.1; NM_001007683.1.
DR   AlphaFoldDB; Q6AYF6; -.
DR   SMR; Q6AYF6; -.
DR   STRING; 10116.ENSRNOP00000024624; -.
DR   GlyGen; Q6AYF6; 1 site.
DR   PaxDb; Q6AYF6; -.
DR   GeneID; 306253; -.
DR   KEGG; rno:306253; -.
DR   UCSC; RGD:1359293; rat.
DR   CTD; 55830; -.
DR   RGD; 1359293; Glt8d1.
DR   VEuPathDB; HostDB:ENSRNOG00000018179; -.
DR   eggNOG; ENOG502QTN8; Eukaryota.
DR   HOGENOM; CLU_010770_0_0_1; -.
DR   InParanoid; Q6AYF6; -.
DR   OrthoDB; 1520602at2759; -.
DR   PRO; PR:Q6AYF6; -.
DR   Proteomes; UP000002494; Chromosome 16.
DR   Bgee; ENSRNOG00000018179; Expressed in pancreas and 20 other tissues.
DR   ExpressionAtlas; Q6AYF6; baseline and differential.
DR   Genevisible; Q6AYF6; RN.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..371
FT                   /note="Glycosyltransferase 8 domain-containing protein 1"
FT                   /id="PRO_0000288530"
FT   TOPO_DOM        1..5
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        6..26
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        27..371
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        257
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   371 AA;  42135 MW;  7C56790EF66FE4EF CRC64;
     MSFRKVTIII WALAVILFLL ALHHNFLSLS SLLRNDVSDS GIVGLQPIDF TANFHQHPVN
     ERQEEIPVVI AASEDRLGGT IAAINSIHQN TRSNVIFYIV TFNRTADHLR SWLNSGSLKS
     IRYKIVNFDT KLLEGKVKED PDQGESMKPL TFARFYLPIL VPSAKKAIYM DDDVIVQGDI
     LALYNTPLKP GHAAAFSEDC DSASTKVMIR GAGNQYNYIG YLDYKKERIR KLSMKASTCS
     FNPGVFVANL TEWKRQNVTN QLEKWMKLNV EEGLYSRTLA GSITTPPLLI VFYQQHSTID
     PMWNVRHLGS SAGKRYSPQF VKAAKLLHWN GHFKPWGRAA SYADVWEKWY IPDPTGKFSL
     IRRHMDTSNI K