ID   GL8D1_XENLA             Reviewed;         364 AA.
AC   Q6DJM3;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 1;
DE            EC=2.4.1.-;
GN   Name=glt8d1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; BC075153; AAH75153.1; -; mRNA.
DR   RefSeq; NP_001086355.1; NM_001092886.1.
DR   AlphaFoldDB; Q6DJM3; -.
DR   SMR; Q6DJM3; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   PRIDE; Q6DJM3; -.
DR   DNASU; 444784; -.
DR   GeneID; 444784; -.
DR   KEGG; xla:444784; -.
DR   CTD; 444784; -.
DR   Xenbase; XB-GENE-6254360; glt8d1.L.
DR   OrthoDB; 1520602at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 444784; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..364
FT                   /note="Glycosyltransferase 8 domain-containing protein 1"
FT                   /id="PRO_0000288532"
FT   TOPO_DOM        1..5
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        6..26
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        27..364
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        102
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        247
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        255
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   364 AA;  41063 MW;  7D625768178D4C90 CRC64;
     MRRVHITVIL LAAVIFLLVL HHNILGLSDI LKRQNSDTGP LVFQRLESLP DAPDIGPEHG
     HGEEIAVVIP GVEERLGGLI ATINSISSNT KSNVVFYIIT TNDTKKHISS WLDGTDLKRV
     AYKLLTFDAR VLDGKVRVDA GAEPVKPMTF ARFYLPSLLP GAKKVIYLDD DVIVQDDIVQ
     LYNTPISPGH AAAFSEDCDS VTSKFPVRGG ANQYNYIGFL DYKKERIRSL GIKANTCSFN
     PGVFVANLTE WRRQNITRQL EKWMELDVTE ELYSKSLSGN IAAPPLLIVF YRLYSNINPL
     WHVRHLGSST GKRYSPQFVK AAKLLHWNGH FKPWGRTSSF PEIWEKWFLP DPSGQFSLIR
     RHAE