ID   GL8D1_XENTR             Reviewed;         371 AA.
AC   Q28I33;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 1;
DE            EC=2.4.1.-;
GN   Name=glt8d1; ORFNames=TEgg066e07.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; CR760617; CAJ81732.1; -; mRNA.
DR   RefSeq; NP_001016586.1; NM_001016586.2.
DR   AlphaFoldDB; Q28I33; -.
DR   SMR; Q28I33; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   GeneID; 549340; -.
DR   KEGG; xtr:549340; -.
DR   CTD; 55830; -.
DR   Xenbase; XB-GENE-6454004; glt8d1.
DR   InParanoid; Q28I33; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..371
FT                   /note="Glycosyltransferase 8 domain-containing protein 1"
FT                   /id="PRO_0000288533"
FT   TOPO_DOM        1..7
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..371
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        104
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        249
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        257
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   371 AA;  42028 MW;  AD741F52E271995E CRC64;
     MSFRKVHIAI ILLAAVVFLL ILHHNILGLT DILTRQSSDS APLVFQRLEA LRDAHESPPE
     ERQGEEIAVV IPGVEERLGG LVAAINSISS NTKSNVVFYI ITTNDTKGHI RSWLDGTGLK
     RVTYKLLAFD TRVLDGKVRV DAGAEPVKPM TFARFYLPNL LPETKKAIYL DDDVIVQDDI
     RDLYNTPLRP GHAAAFSDDC DSVTSKFPVR GAANQYNYIG FLDYKKERIR SLGMRANTCS
     FNPGVFVANL TEWRRQNVTR QLEKWMELDV AEELYSKTLS ASITAPPLLI VFYQRHSNLD
     PLWHVRHLGS SSGKRYSPQF VKAAKLLHWN GHFKPWGRTS SYPEVWEKWF IPDPMGQFAP
     IRRHGEADGT K