ID   GL8D2_BOVIN             Reviewed;         350 AA.
AC   Q2HJ96;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 2;
DE            EC=2.4.1.-;
GN   Name=GLT8D2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; BC113242; AAI13243.1; -; mRNA.
DR   RefSeq; NP_001039731.1; NM_001046266.1.
DR   RefSeq; XP_015326589.1; XM_015471103.1.
DR   AlphaFoldDB; Q2HJ96; -.
DR   SMR; Q2HJ96; -.
DR   STRING; 9913.ENSBTAP00000001224; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   PaxDb; Q2HJ96; -.
DR   Ensembl; ENSBTAT00000001224; ENSBTAP00000001224; ENSBTAG00000000925.
DR   Ensembl; ENSBTAT00000069803; ENSBTAP00000063071; ENSBTAG00000000925.
DR   GeneID; 523294; -.
DR   KEGG; bta:523294; -.
DR   CTD; 83468; -.
DR   VEuPathDB; HostDB:ENSBTAG00000000925; -.
DR   VGNC; VGNC:29424; GLT8D2.
DR   eggNOG; ENOG502QTN8; Eukaryota.
DR   GeneTree; ENSGT00940000158078; -.
DR   HOGENOM; CLU_010770_0_0_1; -.
DR   InParanoid; Q2HJ96; -.
DR   OMA; INPMWHI; -.
DR   OrthoDB; 1520602at2759; -.
DR   TreeFam; TF332433; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000000925; Expressed in trachea and 102 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..350
FT                   /note="Glycosyltransferase 8 domain-containing protein 2"
FT                   /id="PRO_0000271381"
FT   TOPO_DOM        1..6
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..24
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25..349
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        234
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   350 AA;  40184 MW;  64B3D596F8048C5B CRC64;
     MALLRKINQV LLFLLIVTLC GILYKKVHKG TMLRNEADDD SETPEEMEDE IPVVICAAAG
     RMGAAMAAIN SIYSNTDANI LFYVVGLRNT LSRIRKWIEH SKLREINFKI VEFNPVVLKG
     KIRPDSSRPE LLQPLNFVRF YLPLLIHQHE KVIYLDDDVI VQGDIQELYD TTLALGHAAA
     FSDDCDLPSS QDIHRLVGLQ NTYMGYLDYR KKTIKDLGIS PSTCSFNPGV IVANMTEWKH
     QRITKQLEKW MQKNVEENLY SSSLGGGVAT SPMLIVFHGK YSTINPLWHI RHLGWNPDTR
     YSEHFLQEAK LLHWNGRHKP WDFPSVHNDL WESWFVPDPA GIFKLHHPNS