ID   GL8D2_MACFA             Reviewed;         349 AA.
AC   Q4R3U7;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 2;
DE            EC=2.4.1.-;
GN   Name=GLT8D2; ORFNames=QtsA-14057;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; AB179168; BAE02219.1; -; mRNA.
DR   RefSeq; NP_001271625.1; NM_001284696.1.
DR   AlphaFoldDB; Q4R3U7; -.
DR   SMR; Q4R3U7; -.
DR   STRING; 9541.XP_005572113.1; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   GeneID; 101866150; -.
DR   CTD; 83468; -.
DR   eggNOG; ENOG502QTN8; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..349
FT                   /note="Glycosyltransferase 8 domain-containing protein 2"
FT                   /id="PRO_0000271383"
FT   TOPO_DOM        1..6
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..24
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25..349
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        234
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   349 AA;  40006 MW;  D161452E4CAE3CBE CRC64;
     MALLRKINQV LLFLLIVTLC VILYKKVHKG TVSKNDADDE SETPEELEEE IPVVICAAAG
     RMGATMAAIN SIYSNTDANI LFYVVGLRNT LTRIRKWIEH SKLREINFKI VEFNPMVLKG
     KIRPDSSRPE LLQPLNFVRF YLPLLIHQHE KVIYLDDDVI VQGDIHELYD TTLALGHAAA
     FSDDCDLPSA QDINRLVGLQ NTYMGYLDYR KKAIKDLGIS PSTCSFNPGV IVANMTEWKH
     QHITKQLEKW MQKNVEENLY SSSLGGGVAT SPMLIVFHGK YSTINPLWHI RHLGWNPDAR
     YSEHFLQEAK LLHWNGRHKP WDFPSVHNDL WESWFVPDPA GIFKLNHHS