ID   GLB2_ANATR              Reviewed;         146 AA.
AC   P14394;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Globin-2B;
DE   AltName: Full=Globin IIB;
OS   Anadara trapezia (Sydney cockle) (Arca trapezia).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Arcoida; Arcoidea; Arcidae; Anadara.
OX   NCBI_TaxID=6556;
RN   [1]
RP   PROTEIN SEQUENCE.
RA   Fisher W.K., Gilbert A.T., Thompson E.O.P.;
RT   "Amino acid sequence of the globin IIB chain of the dimeric haemoglobin of
RT   the bivalve mollusc Andara trapezia.";
RL   Aust. J. Biol. Sci. 37:191-203(1984).
RN   [2]
RP   VARIANT ASP-64.
RA   Mann R.G., Fisher W.K., Gilbert A.T., Thompson E.O.P.;
RT   "Genetic variation of the dimeric haemoglobin of the bivalve mollusc
RT   Anadara trapezia.";
RL   Aust. J. Biol. Sci. 39:109-115(1986).
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; S06502; HANK2.
DR   AlphaFoldDB; P14394; -.
DR   SMR; P14394; -.
DR   PRIDE; P14394; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR044399; Mb-like_M.
DR   Pfam; PF00042; Globin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport;
KW   Transport.
FT   CHAIN           1..146
FT                   /note="Globin-2B"
FT                   /id="PRO_0000052483"
FT   BINDING         101
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   VARIANT         64
FT                   /note="S -> D (in globin-2A)"
FT                   /evidence="ECO:0000269|Ref.2"
SQ   SEQUENCE   146 AA;  15995 MW;  1D61233F70752D1A CRC64;
     PSVQDAAAQL TADVKKDLRD SWKVLGSDKK GDGMALMTTL FNDHQETIAY FKRMGDVSQG
     MANSKLRGHS ITLMYALQNF IDQLDSTDDL ICVVEKFAVN HITRKISGAE FGKINGPMKK
     VLASKNFGDK YANAWAKLVG VVQAAL