ID   GLB3_MYXGL              Reviewed;         149 AA.
AC   P02209;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Globin-3;
DE   AltName: Full=Hemoglobin III;
OS   Myxine glutinosa (Atlantic hagfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata; Myxini;
OC   Myxiniformes; Myxinidae; Myxininae; Myxine.
OX   NCBI_TaxID=7769;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-149.
RX   PubMed=422122;
RA   Liljeqvist G., Braunitzer G., Paleus S.;
RT   "Hemoglobins, XXVII. The amino acid sequence of hemoglobin III from Myxine
RT   glutinosa L. A new hemecomplex: E7 glutamine, E11 isoleucine.";
RL   Hoppe-Seyler's Z. Physiol. Chem. 360:125-135(1979).
CC   -!- SUBUNIT: Monomer.
CC   -!- MISCELLANEOUS: This globin is the main component in hagfish blood.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; A02530; GGHF3G.
DR   AlphaFoldDB; P02209; -.
DR   SMR; P02209; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR013314; Globin_lamprey/hagfish.
DR   InterPro; IPR044399; Mb-like_M.
DR   PANTHER; PTHR46783; PTHR46783; 1.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR01906; FISHGLOBIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport;
KW   Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..149
FT                   /note="Globin-3"
FT                   /id="PRO_0000052533"
FT   BINDING         104
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   149 AA;  16779 MW;  E23076913CE3C8EB CRC64;
     MPITDHGQPP TLSEGDKKAI RESWPQIYKN FEQNSLAVLL EFLKKFPKAQ DSFPKFSAKK
     SHLEQDPAVK LQAEVIINAV NHTIGLMDKE AAMKKYLKDL STKHSTEFQV NPDMFKELSA
     VFVSTMGGKA AYEKLFSIIA TLLRSTYDA