ID   GLB75_CHITP             Reviewed;         161 AA.
AC   P84299; P02225; P11583;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Globin CTT-VIIB-5/CTT-VIIB-9;
DE   Flags: Precursor;
GN   Name=CTT-7B5; Synonyms=HbVIIB-5;
GN   and
GN   Name=CTT-7B9; Synonyms=HbVIIB-6;
OS   Chironomus thummi piger (Midge) (Chironomus piger).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (CTT-7B5).
RX   PubMed=2841201; DOI=10.1016/0378-1119(88)90344-7;
RA   Hankeln T., Rozynek P., Schmidt E.R.;
RT   "The nucleotide sequence and in situ localization of a gene for a dimeric
RT   haemoglobin from the midge Chironomus thummi piger.";
RL   Gene 64:297-304(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (CTT-7B5 AND CTT-7B9).
RA   Hankeln T., Rozynek P., Schmidt E.R., Broecker M.;
RL   Submitted (SEP-1990) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer.
CC   -!- MISCELLANEOUS: There are at least 12 different components in Midge
CC       globin.
CC   -!- MISCELLANEOUS: There are at least nine genes for VIIB variants.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   EMBL; M20918; AAA28259.1; -; Genomic_DNA.
DR   EMBL; X56271; CAA39714.1; -; Genomic_DNA.
DR   EMBL; X56271; CAA39715.1; -; Genomic_DNA.
DR   PIR; JT0292; JT0292.
DR   AlphaFoldDB; P84299; -.
DR   SMR; P84299; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR002336; Erythrocruorin.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR044399; Mb-like_M.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00611; ERYTHCRUORIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Oxygen transport; Signal; Transport.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000250"
FT   CHAIN           17..161
FT                   /note="Globin CTT-VIIB-5/CTT-VIIB-9"
FT                   /id="PRO_0000011198"
FT   BINDING         76
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         111
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   161 AA;  16945 MW;  EA1BBC8E50A429F4 CRC64;
     MKFFAVLALC IVGAIASPLT ADEASLVQSS WKAVSHNEVE ILAAVFAAYP DIQNKFSQFA
     GKDLASIKDT GAFATHATRI VSFLSEVIAL SGNTSNAAAV NSLVSKLGDD HKARGVSAAQ
     FGEFRTALVA YLQANVSWGD NVAAAWNKAL DNTFAIVVPR L