ID   GLB78_CHITH             Reviewed;         161 AA.
AC   Q23763;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Globin CTT-VIIB-8;
DE   Flags: Precursor;
GN   Name=CTT-7B8;
OS   Chironomus thummi thummi (Midge).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7155;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Larva;
RX   PubMed=7563117; DOI=10.1007/bf01215178;
RA   Trewitt P.M., Luhm R.A., Samad F., Ramakrishnan S., Kao W.-Y., Bergtrom G.;
RT   "Molecular evolutionary analysis of the YWVZ/7B globin gene cluster of the
RT   insect Chironomus thummi.";
RL   J. Mol. Evol. 41:313-328(1995).
CC   -!- SUBUNIT: Homodimer.
CC   -!- MISCELLANEOUS: There are at least 12 different components in Midge
CC       globin.
CC   -!- MISCELLANEOUS: There are at least nine genes for VIIB variants.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   EMBL; U07703; AAA85490.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q23763; -.
DR   SMR; Q23763; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR002336; Erythrocruorin.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR044399; Mb-like_M.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00611; ERYTHCRUORIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Oxygen transport; Signal; Transport.
FT   SIGNAL          1..16
FT   CHAIN           17..161
FT                   /note="Globin CTT-VIIB-8"
FT                   /id="PRO_0000011202"
FT   BINDING         76
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         111
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   161 AA;  17040 MW;  C78B9E70C1F7E161 CRC64;
     MKFFAVLALC IVGAIASPLT ADEASLVQSS WKAVSHNEVE ILAAVFAAYP DIQNKFPQFA
     GKDLASIKDT GAFATHATRI VSFLSEVIAL SGNESNASAV NSLVSKLGDD HKARGVSAAQ
     FGEFRTALVA YLSNHVSWGD NVAAAWNKAL DNTYAIVVPR L