ID   GLBE_CHITH              Reviewed;         152 AA.
AC   P11582;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Globin CTT-E/E';
DE   Flags: Precursor;
GN   Name=CTT-E;
GN   and
GN   Name=CTT-E';
OS   Chironomus thummi thummi (Midge).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7155;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3678833; DOI=10.1016/0378-1119(87)90156-9;
RA   Antoine M., Erbil C., Muench E., Schnell S., Niessing J.;
RT   "Genomic organization and primary structure of five homologous pairs of
RT   intron-less genes encoding secretory globins from the insect Chironomus
RT   thummi thummi.";
RL   Gene 56:41-51(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Hankeln T., Amid C., Weich B., Schmidt E.R.;
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   EMBL; M17604; AAA28253.1; -; Genomic_DNA.
DR   EMBL; M17695; AAA28258.1; -; Genomic_DNA.
DR   EMBL; Y10622; CAA71643.1; -; Genomic_DNA.
DR   AlphaFoldDB; P11582; -.
DR   SMR; P11582; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR002336; Erythrocruorin.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR044399; Mb-like_M.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00611; ERYTHCRUORIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Oxygen transport; Signal; Transport.
FT   SIGNAL          1..15
FT   CHAIN           16..152
FT                   /note="Globin CTT-E/E'"
FT                   /id="PRO_0000011212"
FT   BINDING         73
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         102
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   152 AA;  15964 MW;  52D70B8CF57CFA9E CRC64;
     MKFIILALCV AAASALSGDQ IGLVQSTYGK VKGDSVGILY AVFKADPTIQ AAFPQFVGKD
     LDAIKGGAEF STHAGRIVGF LGGVIDDLPN IGKHVDALVA THKPRGVTHA QFNNFRAAFI
     AYLKGHVDYT AAVEAAWGAT FDAFFGAVFA KM