GLBH_CAEBR
ID GLBH_CAEBR Reviewed; 160 AA.
AC Q27302; A8X390;
DT 27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Globin-like protein;
GN Name=glb-1; Synonyms=cbg-1, glo; ORFNames=CBG06867;
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RA Kloek A.P., Goldberg D.E.;
RL Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16;
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R.M., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: May be a globin and may play a role in oxygen transport.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the globin family. {ECO:0000305}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-3 is the initiator.
CC {ECO:0000305}.
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DR EMBL; U48291; AAA89169.1; -; Genomic_DNA.
DR EMBL; U48290; AAA89169.1; JOINED; Genomic_DNA.
DR EMBL; U48289; AAA89168.1; -; mRNA.
DR EMBL; HE601347; CAP27100.1; -; Genomic_DNA.
DR RefSeq; XP_002642457.1; XM_002642411.1.
DR AlphaFoldDB; Q27302; -.
DR SMR; Q27302; -.
DR STRING; 6238.CBG06867; -.
DR EnsemblMetazoa; CBG06867.1; CBG06867.1; WBGene00000312.
DR GeneID; 8584451; -.
DR KEGG; cbr:CBG_06867; -.
DR CTD; 8584451; -.
DR WormBase; CBG06867; CBP07494; WBGene00000312; Cbr-glb-1.
DR eggNOG; ENOG502SFTY; Eukaryota.
DR HOGENOM; CLU_099979_0_0_1; -.
DR InParanoid; Q27302; -.
DR OMA; DPALWMA; -.
DR OrthoDB; 1370559at2759; -.
DR Proteomes; UP000008549; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd01040; Mb-like; 1.
DR Gene3D; 1.10.490.10; -; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR012085; Globin_nematode.
DR InterPro; IPR044399; Mb-like_M.
DR Pfam; PF00042; Globin; 1.
DR PIRSF; PIRSF002026; Nematode_globin; 1.
DR SUPFAM; SSF46458; SSF46458; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Heme; Iron; Metal-binding; Oxygen transport; Reference proteome;
KW Transport.
FT CHAIN 1..160
FT /note="Globin-like protein"
FT /id="PRO_0000052462"
FT BINDING 101
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="proximal binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 160 AA; 18591 MW; AA301137614D2FA0 CRC64;
MSMTRQEIQD LCVKSLEEKM VGTTDKGIAN GNGFYQYFFT NFPDLRVYFK GAEKFTAEDV
KKSERFDKQG QRILLACHLI ANVFTNEEVF KAYVRETINR HRIYKMDPAL WMAFFTVFTG
YLESTGSLND QQKAAWMALG KEFNAECQVH LKNSNLPYVH
