ID   GLBY_CHITP              Reviewed;         160 AA.
AC   P18968;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Globin CTT-Y;
DE   AltName: Full=HBY;
DE   Flags: Precursor;
GN   Name=CTT-Y;
OS   Chironomus thummi piger (Midge) (Chironomus piger).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2775480; DOI=10.1515/bchm3.1989.370.1.533;
RA   Rozynek P., Hankeln T., Schmidt E.R.;
RT   "Structure of a hemoglobin gene cluster and nucleotide sequence of three
RT   hemoglobin genes from the midge Chironomus thummi piger (Diptera,
RT   Insecta).";
RL   Biol. Chem. Hoppe-Seyler 370:533-542(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Hankeln T., Rozynek P., Schmidt E.R., Broecker M.;
RL   Submitted (SEP-1990) to the EMBL/GenBank/DDBJ databases.
CC   -!- MISCELLANEOUS: There are at least 12 different components in Midge
CC       globin.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   EMBL; X56271; CAA39720.1; -; Genomic_DNA.
DR   PIR; S04498; S04498.
DR   AlphaFoldDB; P18968; -.
DR   SMR; P18968; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR002336; Erythrocruorin.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR044399; Mb-like_M.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00611; ERYTHCRUORIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Oxygen transport; Signal; Transport.
FT   SIGNAL          1..16
FT   CHAIN           17..160
FT                   /note="Globin CTT-Y"
FT                   /id="PRO_0000011209"
FT   BINDING         74
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         109
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   160 AA;  18150 MW;  52DC5ECB8341307B CRC64;
     MKVLAIFALC IIGALATPCD DFKIMQEAWN TMKNEEVEIL YTVFKAYPDI QAKFPQFVGK
     DLETIKGTAE FAVHATRIVS FMTEVISLLG NPDNLPAIMS LLSKLGKDHK GRGITVKQFD
     EFHEAFHNFL HTHSVWNDNV DAAWHCNEKE IRKVINANLE