GLCP_SYNY3
ID GLCP_SYNY3 Reviewed; 468 AA.
AC P15729;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 2.
DT 25-MAY-2022, entry version 150.
DE RecName: Full=Glucose transport protein;
GN Name=gtr; Synonyms=glcP; OrderedLocusNames=sll0771;
OS Synechocystis sp. (strain PCC 6803 / Kazusa).
OC Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC unclassified Synechocystis.
OX NCBI_TaxID=1111708;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2507869; DOI=10.1111/j.1365-2958.1989.tb00272.x;
RA Zhang C.C., Durand M.C., Jeanjean R., Joset F.;
RT "Molecular and genetical analysis of the fructose-glucose transport system
RT in the cyanobacterium Synechocystis PCC6803.";
RL Mol. Microbiol. 3:1221-1229(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2129397; DOI=10.1007/bf00016502;
RA Schmetterer G.R.;
RT "Sequence conservation among the glucose transporter from the
RT cyanobacterium Synechocystis sp. PCC 6803 and mammalian glucose
RT transporters.";
RL Plant Mol. Biol. 14:697-706(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27184 / PCC 6803 / N-1;
RX PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA Sugiura M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT from map positions 64% to 92% of the genome.";
RL DNA Res. 2:153-166(1995).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6803 / Kazusa;
RX PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT genome and assignment of potential protein-coding regions.";
RL DNA Res. 3:109-136(1996).
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; X15988; CAA34119.1; -; Genomic_DNA.
DR EMBL; X16472; CAA34492.1; -; Genomic_DNA.
DR EMBL; BA000022; BAA10117.1; -; Genomic_DNA.
DR PIR; S10014; S10014.
DR AlphaFoldDB; P15729; -.
DR SMR; P15729; -.
DR IntAct; P15729; 9.
DR STRING; 1148.1001492; -.
DR TCDB; 2.A.1.1.32; the major facilitator superfamily (mfs).
DR PaxDb; P15729; -.
DR EnsemblBacteria; BAA10117; BAA10117; BAA10117.
DR KEGG; syn:sll0771; -.
DR eggNOG; COG0477; Bacteria.
DR InParanoid; P15729; -.
DR OMA; WAITASF; -.
DR PhylomeDB; P15729; -.
DR Proteomes; UP000001425; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..468
FT /note="Glucose transport protein"
FT /id="PRO_0000050427"
FT TOPO_DOM 1..17
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 18..38
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 39..58
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 79..84
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 106..114
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 136..149
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 171..186
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 208..265
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 266..286
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 287..307
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 308..328
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 329..331
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 332..352
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 353..366
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 367..387
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 388..412
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 434..436
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 437..457
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 458..468
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CONFLICT 319
FT /note="L -> I (in Ref. 1; CAA34119)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 468 AA; 49748 MW; D7EC545C4FB38D22 CRC64;
MNPSSSPSQS TANVKFVLLI SGVAALGGFL FGFDTAVING AVAALQKHFQ TDSLLTGLSV
SLALLGSALG AFGAGPIADR HGRIKTMILA AVLFTLSSIG SGLPFTIWDF IFWRVLGGIG
VGAASVIAPA YIAEVSPAHL RGRLGSLQQL AIVSGIFIAL LSNWFIALMA GGSAQNPWLF
GAAAWRWMFW TELIPALLYG VCAFLIPESP RYLVAQGQGE KAAAILWKVE GGDVPSRIEE
IQATVSLDHK PRFSDLLSRR GGLLPIVWIG MGLSALQQFV GINVIFYYSS VLWRSVGFTE
EKSLLITVIT GFINILTTLV AIAFVDKFGR KPLLLMGSIG MTITLGILSV VFGGATVVNG
QPTLTGAAGI IALVTANLYV FSFGFSWGPI VWVLLGEMFN NKIRAAALSV AAGVQWIANF
IISTTFPPLL DTVGLGPAYG LYATSAAISI FFIWFFVKET KGKTLEQM
