ID   GLCTK_DANRE             Reviewed;         502 AA.
AC   Q08BL7;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Glycerate kinase;
DE            EC=2.7.1.31;
GN   Name=glyctk; ORFNames=zgc:153346;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+);
CC         Xref=Rhea:RHEA:23516, ChEBI:CHEBI:15378, ChEBI:CHEBI:16659,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216;
CC         EC=2.7.1.31; Evidence={ECO:0000250|UniProtKB:Q8IVS8};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8IVS8}.
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-2 family.
CC       {ECO:0000305}.
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DR   EMBL; BC124662; AAI24663.1; -; mRNA.
DR   AlphaFoldDB; Q08BL7; -.
DR   SMR; Q08BL7; -.
DR   STRING; 7955.ENSDARP00000124654; -.
DR   PaxDb; Q08BL7; -.
DR   ZFIN; ZDB-GENE-061013-308; glyctk.
DR   eggNOG; KOG3935; Eukaryota.
DR   InParanoid; Q08BL7; -.
DR   PhylomeDB; Q08BL7; -.
DR   Reactome; R-DRE-70350; Fructose catabolism.
DR   PRO; PR:Q08BL7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008887; F:glycerate kinase activity; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   Gene3D; 3.40.1480.10; -; 1.
DR   Gene3D; 3.40.50.10180; -; 1.
DR   InterPro; IPR037035; GK-like_C_sf.
DR   InterPro; IPR038614; GK_N_sf.
DR   InterPro; IPR007835; MOFRL.
DR   InterPro; IPR025286; MOFRL_assoc_dom.
DR   InterPro; IPR039760; MOFRL_protein.
DR   PANTHER; PTHR12227; PTHR12227; 1.
DR   Pfam; PF13660; DUF4147; 1.
DR   Pfam; PF05161; MOFRL; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome;
KW   Transferase.
FT   CHAIN           1..502
FT                   /note="Glycerate kinase"
FT                   /id="PRO_0000287196"
SQ   SEQUENCE   502 AA;  52608 MW;  5B2166503C38BA29 CRC64;
     MSSLNTRARA VFSAAVEGVH PDMVVRRGLE RHGDKLHVGG QSFTLTNNLY LVGFGKAVLG
     MAAEAERIVG DHLIKGVVSV PHGIQNTLRS HGKEKMLLES NSRITVMEGA KHNLPDTDAQ
     KSAECIRDLA SSLTEKDLLL VLISGGGSAL LPAPAPPMSL QEKQDVTRKL AAAGATIQEL
     NTVRRALSLL KGGGLAQCAS PAKVVALILS DVIGDPLDLI ASGPTVRSDS SPEEVWAILD
     NYKLSDSLPS SVKEVLSKSI SGQGSGVKNQ PQEVKDNVLN VVIGSNTIAL ECASRKASEL
     GLRPVILSPG VCGDVRSVAR LYGLLSSFAC SPGKEPPPEL AAEILKLGPE VGIESWDLCR
     TMNVLVGERK EGWGATCLLA GGEPTVKLSG KGRGGRNQEL AMRVGLELSQ GEVKSGAVFL
     SGGTDGQDGP TEAAGAVADG ELKEEAASQG LDTDSFLANN DSFTFFSKLS EGRRLLNPGL
     TGTNVMDVHV MLLPPSPQKD LQ