ID   GLCU_BACAN              Reviewed;         285 AA.
AC   Q81KM7; Q6HS29; Q6KLD3;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Probable glucose uptake protein GlcU;
GN   Name=glcU; OrderedLocusNames=BA_4969, GBAA_4969, BAS4613;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the uptake of glucose. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
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DR   EMBL; AE016879; AAP28650.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT34091.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT56909.1; -; Genomic_DNA.
DR   RefSeq; NP_847164.1; NC_003997.3.
DR   RefSeq; WP_000350855.1; NZ_WXXJ01000026.1.
DR   RefSeq; YP_030859.1; NC_005945.1.
DR   AlphaFoldDB; Q81KM7; -.
DR   SMR; Q81KM7; -.
DR   STRING; 260799.BAS4613; -.
DR   DNASU; 1084185; -.
DR   EnsemblBacteria; AAP28650; AAP28650; BA_4969.
DR   EnsemblBacteria; AAT34091; AAT34091; GBAA_4969.
DR   GeneID; 45024587; -.
DR   KEGG; ban:BA_4969; -.
DR   KEGG; bar:GBAA_4969; -.
DR   KEGG; bat:BAS4613; -.
DR   PATRIC; fig|198094.11.peg.4929; -.
DR   eggNOG; COG4975; Bacteria.
DR   HOGENOM; CLU_076024_0_0_9; -.
DR   OMA; VNTKMGG; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..285
FT                   /note="Probable glucose uptake protein GlcU"
FT                   /id="PRO_0000213619"
FT   TRANSMEM        4..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        232..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  30520 MW;  CD02250500ACF2E3 CRC64;
     MDIFLAILPA IFWGSIVLFN VKLGGGPYSQ TLGTTFGALI FSIVVYIFMK PVLTPTVIGV
     GIVSGLFWAL GQANQLKSID LMGVSRTMPI STGLQLVSTT LFGVIVFHEW STIISVVLGV
     LALVCIIIGV ILTSLQSEEE KNAEQAGNFK RGIIILLIST VGYLVYVVVI RLFNVDGWSA
     LLPQAVGMVL GGILLTFKHH PFNKYAIRNI IPGLIWAAGN MFLFISQPRV GVATSFSLSQ
     MGIIISTLGG ILILGERKTK RQLTGIVVGI VFIIAAGIML GIAKS