GLCU_BACCR
ID GLCU_BACCR Reviewed; 286 AA.
AC Q816V0;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Probable glucose uptake protein GlcU;
GN Name=glcU; OrderedLocusNames=BC_4716;
OS Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC
OS 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=226900;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373
RC / NCTC 2599 / NRRL B-3711;
RX PubMed=12721630; DOI=10.1038/nature01582;
RA Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V.,
RA Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M.,
RA Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G.,
RA Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.;
RT "Genome sequence of Bacillus cereus and comparative analysis with Bacillus
RT anthracis.";
RL Nature 423:87-91(2003).
CC -!- FUNCTION: Involved in the uptake of glucose. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC {ECO:0000305}.
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DR EMBL; AE016877; AAP11621.1; -; Genomic_DNA.
DR RefSeq; NP_834420.1; NC_004722.1.
DR AlphaFoldDB; Q816V0; -.
DR STRING; 226900.BC_4716; -.
DR EnsemblBacteria; AAP11621; AAP11621; BC_4716.
DR KEGG; bce:BC4716; -.
DR PATRIC; fig|226900.8.peg.4878; -.
DR HOGENOM; CLU_076024_0_0_9; -.
DR OMA; VNTKMGG; -.
DR Proteomes; UP000001417; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR010651; Sugar_transport.
DR PANTHER; PTHR16119; PTHR16119; 2.
DR Pfam; PF06800; Sugar_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..286
FT /note="Probable glucose uptake protein GlcU"
FT /id="PRO_0000213621"
FT TRANSMEM 4..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 27..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..255
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 267..284
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 286 AA; 30595 MW; D418EDA1F9C778CD CRC64;
MMDIFLAILP AIFWGSIVLF NVKLGGGPYS QTLGTTFGAL IFSIVVYIFM KPVLTPTVIG
VGVVSGLFWA LGQANQLKSI DLMGVSRTMP ISTGLQLVAT TLFGVIVFHE WSTTISVVLG
ILALVCIIIG VILTSLQSEE EKNAEQAANF KRGIVILLIS TVGYLVYVVV IRLFNVDGWS
ALLPQAVGMV LGGILLTFKH HPFNKYAIRN IIPGLIWAAG NMFLFISQPR VGVATSFSLS
QMGIIISTLG GILILGEKKT KRQLTGIVVG IVFIIAAGIM LGIAKS
