ID   GLCU_PRIMG              Reviewed;         286 AA.
AC   P40419;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Probable glucose uptake protein GlcU;
GN   Name=glcU;
OS   Priestia megaterium (Bacillus megaterium).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Priestia.
OX   NCBI_TaxID=1404;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IAM 1030 / JCM 20016;
RA   Mitamura T., Ebora R.V., Nakai T., Makino Y., Negoro S., Urabe I.,
RA   Okada H.;
RT   "Structure of isozyme genes of glucose dehydrogenase from Bacillus
RT   megaterium IAM1030.";
RL   J. Ferment. Bioeng. 70:363-369(1990).
CC   -!- FUNCTION: Involved in the uptake of glucose. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during sporulation.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D90043; BAA14098.1; -; Genomic_DNA.
DR   PIR; I39851; JS0384.
DR   RefSeq; WP_013081864.1; NZ_JABXFF010000013.1.
DR   AlphaFoldDB; P40419; -.
DR   SMR; P40419; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Sporulation; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..286
FT                   /note="Probable glucose uptake protein GlcU"
FT                   /id="PRO_0000213622"
FT   TRANSMEM        4..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   286 AA;  30490 MW;  95AB89D02511D74D CRC64;
     MDIFLAVLPA IFWGSIVLFN VKLGGGPYSQ TLGTTLGALI FSIGIYIFVH PTFTPLIFGV
     GVVSGLFWAV GQSNQLKSID LIGVSKTMPI STGLQLVSTS LFGVIVFHEW STKTSIILGV
     LALIFIIVGI VLASLQSKEE KEAEEGKGNF KKGIVILLIS TVGYLVYVVV ARLFNVDGWS
     ALLPQAIGMV IGGVLLTFKH KPFNKYAIRN IIPGLIWAAG NMFLFISQPK VGVATSFSLS
     QMGIVISTLG GIIILGEKKT KRQLVGIIIG IILIIIAGVM LGLAKS