ID   GLGA1_GEOSL             Reviewed;         501 AA.
AC   Q74ED9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Glycogen synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA1 {ECO:0000255|HAMAP-Rule:MF_00484}; Synonyms=glgA-1;
GN   OrderedLocusNames=GSU1023;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AE017180; AAR34350.1; -; Genomic_DNA.
DR   RefSeq; NP_952077.1; NC_002939.5.
DR   RefSeq; WP_010941686.1; NC_002939.5.
DR   AlphaFoldDB; Q74ED9; -.
DR   SMR; Q74ED9; -.
DR   STRING; 243231.GSU1023; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   PRIDE; Q74ED9; -.
DR   EnsemblBacteria; AAR34350; AAR34350; GSU1023.
DR   KEGG; gsu:GSU1023; -.
DR   PATRIC; fig|243231.5.peg.1023; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_7; -.
DR   InParanoid; Q74ED9; -.
DR   OMA; CGWVHGR; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IBA:GO_Central.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..501
FT                   /note="Glycogen synthase 1"
FT                   /id="PRO_0000188617"
FT   BINDING         18
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   501 AA;  56222 MW;  8D89020F288AB2DB CRC64;
     MTRLNILMAA SECVPFAKEG GLADVVGVLP KYLAHMGHDV RVVMPLYSRI DPERFGLERL
     PGVLVVPMGI MGNQYCGVWE GRLPGSAVPV YFLEHEGYYG REGLYEEDNV GYMDNDNRFI
     FLSRAAMELP KLIGFAPDVF HAHDWHTAAV PVFLNTLYRD DPLVGGAASV LTVHNMQHQG
     NFYPGAMEVL GIGWEHFTFL GLEKDNQTNL LKGGLYHATV LNTVSEGYAR EMQTPEYGWG
     LDGVVRARSA DLVGILNGVD YEEWNPETDP HIVANYSRSD LSGKKLCKRD VQRFFGLPER
     DDVPLFGLVG RLVKQKGIDI LAEAIHRILA LDVQVVMLGA GEPWSHFYFG DVRNEYPEKF
     GLYIGYNNGL SHRIEAGSDF FVMPSAFEPC GLNQMYSLRY GTLPIVRATG GLDDSVENFD
     EQNLTGNGFK FWSHDADALF DTVGWTVHTW YRRKDAMAAL IGNAMAKRFT WEDSAARYEE
     LYCRALRKRL GVGVFVRRFG G