ID   GLGA1_NOSS1             Reviewed;         472 AA.
AC   Q8YVU5;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Glycogen synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA1 {ECO:0000255|HAMAP-Rule:MF_00484}; Synonyms=glgA;
GN   OrderedLocusNames=alr1879;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; BA000019; BAB73578.1; -; Genomic_DNA.
DR   PIR; AI2040; AI2040.
DR   RefSeq; WP_010996043.1; NZ_RSCN01000017.1.
DR   AlphaFoldDB; Q8YVU5; -.
DR   SMR; Q8YVU5; -.
DR   STRING; 103690.17130969; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; BAB73578; BAB73578; BAB73578.
DR   KEGG; ana:alr1879; -.
DR   eggNOG; COG0297; Bacteria.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..472
FT                   /note="Glycogen synthase 1"
FT                   /id="PRO_0000188587"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   472 AA;  54252 MW;  1DDD510EE3F0F55D CRC64;
     MRILFVAAEA APIAKVGGMG DVVGALPKVL RKMGHDVRIF LPYYGFLPDK MEIPKDPIWK
     GYAMFQDFTV HEAVLPGTDV PLYLFGHPAF TPRRIYSGDD EDWRFTLFSN GAAEFCWNYW
     KPDIIHCHDW HTGMIPVWMN QSPDITTVFT IHNLAYQGPW RWYLDKITWC PWYMQGHNTM
     AAAVQFADRV NTVSPTYAEQ IKTPAYGEKI EGLLSFISGK LSGIVNGIDT EVYDPANDKY
     IAQTFTADTL DKRKANKIAL QEEVGLEVNS NAFLIGMVTR LVEQKGLDLV IQMLDRFMAY
     TDAQFVLLGT GDRYYETQMW QLASRYPGRM ATYLLYNDAL SRRIYAGTDA FLMPSRFEPC
     GISQMMALRY GSIPIVRRTG GLVDTVSHHD PINEAGTGYC FDRYEPLDLF TCMIRAWEGF
     RYKPQWQELQ KRGMSQDFSW YKSAKEYDKL YRSMYGLPDP EETQPELILT NQ