GLGA1_SYNJA
ID GLGA1_SYNJA Reviewed; 491 AA.
AC Q2JSZ9;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Glycogen synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA1 {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=CYA_2071;
OS Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone
OS A-Prime).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC unclassified Synechococcus.
OX NCBI_TaxID=321327;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA-3-3Ab;
RX PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N.,
RA Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT "Population level functional diversity in a microbial community revealed by
RT comparative genomic and metagenomic analyses.";
RL ISME J. 1:703-713(2007).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000239; ABD00211.1; -; Genomic_DNA.
DR RefSeq; WP_011430885.1; NC_007775.1.
DR AlphaFoldDB; Q2JSZ9; -.
DR SMR; Q2JSZ9; -.
DR STRING; 321327.CYA_2071; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABD00211; ABD00211; CYA_2071.
DR KEGG; cya:CYA_2071; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_3_3; -.
DR OMA; CGWVHGR; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000008818; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..491
FT /note="Glycogen synthase 1"
FT /id="PRO_0000241804"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 491 AA; 57039 MW; 836DE01B097200F9 CRC64;
MYIVQIASEC APVIKAGGLG DVVYGLSREL EVRGHCVELV LPKYDTMRYD QIWGLHDAYR
DLWVPWYGGA IHCSVYCGWV HGRLCFFIEP HSGDNFFNRG CYYGCPDDNM RFAFFSKAAL
EFLLKSNKRP DIIHCHDWQT GLVPVLLFEI YKYHGMENQR VCYTIHNFKH QGFGGPEILW
ATGLNREPYY FHYDRLRDNF NPFALNFMKG GIVFSNFVTT VSPTHALEAR FGNYNYGLGH
TLYLHQHKFR GVLNGIDYDI WNPEIDRFIP FHYTAQTLEN KAKNKKALRD QLWLQDVDKP
IVAYIGRLDE QKGVHLVHHA IYRSLFKNAQ FVLLGSATEP GIGAWFAHEK RYLNDNPDVH
IELGFNEELS HLIYAGADIL VVPSHYEPCG LTQMIGLKYG TVPVVRGVGG LVDTVFDRDY
DTRKLPEQRN GYVFYHTDRA ALESALDRAI DLWYTAPDQF RQLQVQGMSY DYSWNYPGKE
YLEIYEFIRH R
