ID   GLGA1_TRIV2             Reviewed;         492 AA.
AC   Q3M9U1;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Glycogen synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA1 {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Ava_2631;
OS   Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29413 / PCC 7937;
RX   PubMed=25197444; DOI=10.4056/sigs.3899418;
RA   Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA   Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT   "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL   Stand. Genomic Sci. 9:562-573(2014).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; CP000117; ABA22245.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q3M9U1; -.
DR   SMR; Q3M9U1; -.
DR   STRING; 240292.Ava_2631; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; ABA22245; ABA22245; Ava_2631.
DR   KEGG; ava:Ava_2631; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_3_3; -.
DR   OMA; CGWVHGR; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000002533; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..492
FT                   /note="Glycogen synthase 1"
FT                   /id="PRO_0000230232"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   492 AA;  56911 MW;  9D278F0340F92643 CRC64;
     MYIVQIASEC APVIKAGGLG DVVYGLSREL EIRGNCVELI LPKYDCMRYD HIWGLHEAYL
     NLWVPWFGAA IHCTVYCGWV HGRVCFFIEP HSEDNFFNRG CYYGCDDDDM RFAFFSKAAL
     EFLHQSNKRP DIIHCHDWQT GLVPVMLYEI YKYHGMDTQR VCYTIHNFKH QGIGGVKTLW
     ATGLNREAYY FQNDKLQDDF NPFALNYMKG GIVYSNAVTT VSPNHALEAQ YTDVGCGLGH
     TLYQHKDKFS GILNGIDYDF WNPEIDRYIP YNYNQEDFEQ KLYNKKALRE RLLLQAADKP
     IIAYIGRLDN QKGVHLVHHA IYHSLNKGAQ FVLLGSATEA GINAHFRHEK QFLNNNPDVH
     LELGFNEELS HLIYAGADMI VVPSNYEPCG LTQMIGLKYG TVPIVRGVGG LVNTVFDRDY
     DQNLPPEKRN GYVFYQSDNQ ALESAMNRAI DLWYQSPEKF QQLAIQGMKY DYSWNNPGKE
     YLDIYEWIKY KW