ID   GLGA2_AGRFC             Reviewed;         509 AA.
AC   Q8UK38;
DT   19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   19-OCT-2002, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Glycogen synthase 2;
DE            EC=2.4.1.21;
DE   AltName: Full=Starch [bacterial glycogen] synthase 2;
GN   Name=glgA2; OrderedLocusNames=Atu5285; ORFNames=AGR_pAT_410;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid AT.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE007872; AAK90661.1; -; Genomic_DNA.
DR   PIR; AH3194; AH3194.
DR   RefSeq; NP_396220.1; NC_003064.2.
DR   RefSeq; WP_010974543.1; NC_003064.2.
DR   AlphaFoldDB; Q8UK38; -.
DR   SMR; Q8UK38; -.
DR   STRING; 176299.Atu5285; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; AAK90661; AAK90661; Atu5285.
DR   KEGG; atu:Atu5285; -.
DR   PATRIC; fig|176299.10.peg.4960; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_4_5; -.
DR   OMA; MPSRWEP; -.
DR   PhylomeDB; Q8UK38; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000813; Plasmid At.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Plasmid; Reference proteome;
KW   Transferase.
FT   CHAIN           1..509
FT                   /note="Glycogen synthase 2"
FT                   /id="PRO_0000188585"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   509 AA;  55309 MW;  E2D12821F286FA53 CRC64;
     MRILAVTAEM FPFVKTGGLA DATSALPQAL ERKGADVRTL LPLYRGLTPL VRGRKPVLVA
     NILEQPVSVY YVVSDGHKLL LLEAASLFDR DGHPYGVKGE PFADNDLRFA VLSKVAAEIA
     LGAIDGWQPD VVHVHDWHAA LTCVYLADST PSVASVLTLH NLAFQGQYPL ERAGMLGLPS
     HLCTVDCLEY YDDMSFLKGG LTTASAVTTV SPTYAREILT PEMGMGMHGV LARRRGDLRG
     IVNGVDHDVW NPATDPYILA NFTAATATRR SLNKYALLQA LGLAPTQGPV FGVVSRLTWQ
     KGIDLLPHVV PLIIERKGRL IVHGEGDTAL EDSLQALAKR YPELVCAHIG YDERLAHMIQ
     AGSDFIIQPS RFEPCGLTQL YALRYGALPI VSRTGGLAET IIDANDAAIE AGVATGFQFE
     PANEDDLRAA LERAISAYND RELFRRLQTQ AMQANFSWDK SAAQYMALFE SLVGNSTRET
     DAVADIRTET FAKIRADRRL AGTPGSPTG