ID   GLGA2_GEOSL             Reviewed;         484 AA.
AC   Q747K8;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Glycogen synthase 2 {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase 2 {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA2 {ECO:0000255|HAMAP-Rule:MF_00484}; Synonyms=glgA-2;
GN   OrderedLocusNames=GSU3257;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AE017180; AAR36648.1; -; Genomic_DNA.
DR   RefSeq; NP_954298.1; NC_002939.5.
DR   RefSeq; WP_010943869.1; NC_002939.5.
DR   AlphaFoldDB; Q747K8; -.
DR   SMR; Q747K8; -.
DR   STRING; 243231.GSU3257; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; AAR36648; AAR36648; GSU3257.
DR   KEGG; gsu:GSU3257; -.
DR   PATRIC; fig|243231.5.peg.3274; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_5_7; -.
DR   InParanoid; Q747K8; -.
DR   OMA; TWCPWYM; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IBA:GO_Central.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..484
FT                   /note="Glycogen synthase 2"
FT                   /id="PRO_0000188618"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   484 AA;  54142 MW;  B06056E2B64EFBE5 CRC64;
     MKVLMVASEV APFARTGGLA EVTAALPAAL RRMGHDVRVI MPFYRCAAQT ELGVRKARKS
     AEVSLNGETH KGFLRQAALG DVPVYLVENR EFFSRDYLYG TPEGDYPDNP RRFAFFCRSV
     LQFLKRMDFR PDVIHCHDWQ TALIPIILRL EAADDPFFAR TATVFTIHNL AYQGLFPAPA
     IAETGLPSAL FTTEWLEYYG QLNLMKGAIL TADLITTVSE TYRREIMTPT QGCGLEGVLA
     RRGDDLFGIV NGIDTDEWNP AADKRIFRNY SARALAGKAA DKLELQRELG MPAAPSVPLI
     GMVSRLAEQK GIDLVLELLP RLAESELQFV LLGTGNACYL ERLNSFRSKG AANISINLGF
     NDPLAPKIYA GSDLFLMPSR FEPCGLSQLI AMRYGTVPVV RHTGGLRDTV VDVTRHPREG
     TGFTFEDFTA DACWEAIERA LAGYRDRESW RRIMRRGMHR DVSWHNAAGR YETLYRMAAD
     TRRG