GLGA2_RHIME
ID GLGA2_RHIME Reviewed; 486 AA.
AC P58394;
DT 16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2001, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Glycogen synthase 2;
DE EC=2.4.1.21;
DE AltName: Full=Starch [bacterial glycogen] synthase 2;
GN Name=glgA2; OrderedLocusNames=RB1411; ORFNames=SMb20704;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OG Plasmid pSymB (megaplasmid 2).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481431; DOI=10.1073/pnas.161294698;
RA Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT endosymbiont Sinorhizobium meliloti.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000305}.
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DR EMBL; AL591985; CAC49811.1; -; Genomic_DNA.
DR PIR; C96018; C96018.
DR RefSeq; NP_437951.1; NC_003078.1.
DR RefSeq; WP_010976226.1; NC_003078.1.
DR AlphaFoldDB; P58394; -.
DR SMR; P58394; -.
DR STRING; 266834.SM_b20704; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAC49811; CAC49811; SM_b20704.
DR GeneID; 25013601; -.
DR GeneID; 61601320; -.
DR KEGG; sme:SM_b20704; -.
DR PATRIC; fig|266834.11.peg.6332; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_5; -.
DR OMA; MPSRWEP; -.
DR UniPathway; UPA00164; -.
DR PRO; PR:P58394; -.
DR Proteomes; UP000001976; Plasmid pSymB.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Plasmid; Reference proteome;
KW Transferase.
FT CHAIN 1..486
FT /note="Glycogen synthase 2"
FT /id="PRO_0000188638"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000250"
SQ SEQUENCE 486 AA; 53635 MW; 0068BAF9E8EFE805 CRC64;
MQILSVTAEI FPLVKTGGLA DVAGSLPKAL RAHGIHTRSF VPGYPGVMRA LSDATPVAEF
ESLFGERATL IAARAHGLDL FVLDAPAFYD RQGALYVDRH GRDYADNWKR FAAFSLVASQ
IARGLVPNWR PHIIHAHDWH AAMSLLYLKY AGDDTIPRVL TVHNLAFQGQ FPAHYFPELG
LPAEAYSIDG VEYYGDIGFL KGGLQAADAI TVVSPTYARE IMSPAFGMGL EGVMNERHAD
VVGIVNGIDL EVWDPSSDPC IEHHYSARVP LRRLPNRQVL LRHFGLPDTC GPIFASVNRL
TWQKGMDLLA ATAGEIVKNG GTLIIHGQGE EKLEAAFMDL MRRFPQNISV SIGYDEHLAH
RIHAGADAML VPSRFEPCGL TQLYALRYGC VPVVARTGGL SETIIDANDA ALHAHVATGI
QFAPIDEDGL RHALRRTFRL YRLRRVWEGL RRQGMKTDCS WHRSAARYAD LYSELLNPDM
RLVGSA
