GLGA2_SYNY3
ID GLGA2_SYNY3 Reviewed; 491 AA.
AC P72623;
DT 16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Probable glycogen synthase 2;
DE EC=2.4.1.21;
DE AltName: Full=Starch [bacterial glycogen] synthase 2;
GN Name=glgA2; OrderedLocusNames=sll1393;
OS Synechocystis sp. (strain PCC 6803 / Kazusa).
OC Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC unclassified Synechocystis.
OX NCBI_TaxID=1111708;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6803 / Kazusa;
RX PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT genome and assignment of potential protein-coding regions.";
RL DNA Res. 3:109-136(1996).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000305}.
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DR EMBL; BA000022; BAA16625.1; -; Genomic_DNA.
DR PIR; S74473; S74473.
DR AlphaFoldDB; P72623; -.
DR SMR; P72623; -.
DR IntAct; P72623; 6.
DR STRING; 1148.1651697; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR PaxDb; P72623; -.
DR EnsemblBacteria; BAA16625; BAA16625; BAA16625.
DR KEGG; syn:sll1393; -.
DR eggNOG; COG0297; Bacteria.
DR InParanoid; P72623; -.
DR OMA; CGWVHGR; -.
DR PhylomeDB; P72623; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001425; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..491
FT /note="Probable glycogen synthase 2"
FT /id="PRO_0000188656"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000250"
SQ SEQUENCE 491 AA; 56225 MW; 9AE25BB6D0CF4B5A CRC64;
MYIVQIASEC APVIKAGGLG DVIYGLSREL ELRGHCVELI LPMYDCMRYD HIWGLHDAYR
NLEVPWYGSS IFCDVFCGWV HGRLCFFIQP KSSDNFFNRG HYYGALDDHM RFAFFSKAAM
EFLLRSNKRP DIIHCHDWQT GLVPVLLYEI YRFHGMDHQR VCYTIHNFKH QGIAGANILH
ATGLNNDSYY FSYDRLQDNF NPNAINFMKG GIVYSNYVNT VSPHHAWEAR FSDISCGLGH
TLEIHQQKFG GILNGLDYEV WNPEIDPLLA SNFSVKTFGD KAKNKQALRE RLLLETDDKK
PMLCFIGRLD GQKGVHLVHH SIYYALSQGA QFVLLGSATE PNLSKWFWHE KQHLNDNPNV
HLELGFDEEL AHLIYGAADI IVVPSNYEPC GLTQMIGLRY GAVPVVRGVG GLVNTVFDRD
YDQNHPPEKR NGFVFYQPDE YALETALSRA IALYKDDPVA FKTLALQGMA YDYSWNKPGL
QYVEAYEYIR A
