ID   GLGA_ALIF1              Reviewed;         487 AA.
AC   Q5DZC1;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 2.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=VF_A0805;
OS   Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=312309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700601 / ES114;
RX   PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA   Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA   Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA   Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT   "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT   pathogenic congeners.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAW87875.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000021; AAW87875.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_047863328.1; NC_006841.2.
DR   RefSeq; YP_206763.1; NC_006841.2.
DR   AlphaFoldDB; Q5DZC1; -.
DR   SMR; Q5DZC1; -.
DR   STRING; 312309.VF_A0805; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; AAW87875; AAW87875; VF_A0805.
DR   KEGG; vfi:VF_A0805; -.
DR   PATRIC; fig|312309.11.peg.3407; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_6; -.
DR   OrthoDB; 83240at2; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000537; Chromosome II.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..487
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000230271"
FT   BINDING         20
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   487 AA;  54916 MW;  D0B33A80244A2F4C CRC64;
     MVTKTLSIVF VASEVDGLIK SGGLADVAKA LPKSLKELGH SVQIVMPAYK TIAGRDDAEI
     ILTTQLEHWP HTAYQVRSLN VDGIPVFAIE SGDYFERAEM YAENNQAYAD NGERFAFFSA
     ATLDLLPKLL NKKPDIIHVN DWHTGLIPYL LKKRYVENEF YHQTRSVLSI HNAVFKGIFH
     YDEIACLSEF KSHFVPEASI SHTHVSMLKA GVQCADKINA VSPNYAKELL TELGSHGMAS
     DFQDRESDLI GILNGCDYSE WNPEKDSYIP KQFKVNRISM VRGKKACKAA LQQELSLPQK
     DVAMYGMVCR LTNQKGIQYL LPILEQFLKN DLQLVIVGTG DPVLATRLTE IAQEHSDKFA
     FVEAYDNKLA HWVEAGSDFF IMPSEFEPCG LNQIYSMAYG TLPIVREVGG LKDSVNNYDD
     DIENATGFSF KNPEPMELLL VLMRSLLLYS QNLNEVKRVQ LHAMKQDFCW NKAALKYIEM
     YRTAINS