GLGA_ALIFM
ID GLGA_ALIFM Reviewed; 487 AA.
AC B5EUW2;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2008, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=VFMJ11_A0932;
OS Aliivibrio fischeri (strain MJ11) (Vibrio fischeri).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Aliivibrio.
OX NCBI_TaxID=388396;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MJ11;
RA Mandel M.J., Stabb E.V., Ruby E.G., Ferriera S., Johnson J., Kravitz S.,
RA Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RT "Complete sequence of Vibrio fischeri strain MJ11.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001133; ACH64090.1; -; Genomic_DNA.
DR RefSeq; WP_012535224.1; NC_011186.1.
DR AlphaFoldDB; B5EUW2; -.
DR SMR; B5EUW2; -.
DR EnsemblBacteria; ACH64090; ACH64090; VFMJ11_A0932.
DR KEGG; vfm:VFMJ11_A0932; -.
DR HOGENOM; CLU_009583_18_2_6; -.
DR OMA; CGWVHGR; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001857; Chromosome II.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..487
FT /note="Glycogen synthase"
FT /id="PRO_1000126111"
FT BINDING 20
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 487 AA; 54865 MW; 938D16569F0ED9A8 CRC64;
MVTKTLSIVF VASEVDGLIK SGGLADVAKA LPKSLKELGH SVQIVMPAYK TIAGRDDAEI
ILTTQLEHWP HTAYQVRSLS IDGISVFAIE SGDYFERAEM YAENNQAYAD NGERFAFFSA
ATLDLLPKLL NKKPDIIHVN DWHTGLIPYL LKKRYAENEF YHQTRSVLSI HNAVFKGIFH
YDEIACLSEF KSHFVPEASI SHTHVSMLKA GVQCADKINA VSPNYAKELL TELGSHGMAS
DFQDRESDLI GILNGCDYSE WNPEKDSYIP KQFKVNRISM VRGKKACKAA LQQEVSLPQK
DVAMYGMVCR LTNQKGIQYL LPILEQFLKN DLQLVIVGTG DPVLAARLTE IAQEHSDKFA
FIEAYDNKLA HWVEAGSDFF IMPSEFEPCG LNQIYSMAYG TLPIVREVGG LKDSVNNYDD
DIENATGFSF KNPEPMELLL VLMRSLLLYS QNLNEVKRVQ LHAMKQDFCW NKAALKYIEM
YRTTINS
