GLGA_ANASK
ID GLGA_ANASK Reviewed; 475 AA.
AC B4ULD8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=AnaeK_0142;
OS Anaeromyxobacter sp. (strain K).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter;
OC unclassified Anaeromyxobacter.
OX NCBI_TaxID=447217;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G.,
RA Beliaev A.;
RT "Complete sequence of Anaeromyxobacter sp. K.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001131; ACG71385.1; -; Genomic_DNA.
DR RefSeq; WP_012524221.1; NC_011145.1.
DR AlphaFoldDB; B4ULD8; -.
DR SMR; B4ULD8; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACG71385; ACG71385; AnaeK_0142.
DR KEGG; ank:AnaeK_0142; -.
DR HOGENOM; CLU_009583_18_2_7; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001871; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..475
FT /note="Glycogen synthase"
FT /id="PRO_1000126053"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 475 AA; 51778 MW; B09202DB154471A2 CRC64;
MQILFVASEV GPWSKTGGLG DVAGALPQAL AERGNEVAVV TPRHGSIDPR AAGLQPVRTA
LQVRGEPVSL WVKRGPAPVY FVEHPHLFGN RRGLYGEGGR DHGDNAERFA FLTRAALALP
GALGLRPRIL HLNDWQCGLG PWLLRHEHAR DPALAGARTV FTIHNLAYQG LFPKQVLPAL
GLPWEVFRWE AMEFFDQLSF MKAGLAFADA LTTVSPTYAR EILTPEGGAS LDALLRHRAR
DLHGILNGID VHAWDPARDP HLPAHFTAGD LAGKAACKAA LQREVGLPVR PEVPVAGLVT
RLAEQKGIDL VAAALPALLA RDVQVVLLGS GDPAYQETFA RAAREHPDRV AARIGFDEGL
AHRIEAGADL FLMPSRFEPC GLNQMYSLRY GTVPVVRAVG GLADTVEDFD GVARGTGFRF
SEYTPQALLT ATRRALDVFR DRRAWRGLVE RGMAEDNSWE RSAARYEALY RTLAP
