GLGA_AROAE
ID GLGA_AROAE Reviewed; 494 AA.
AC Q5NXZ7;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=AZOSEA39420;
GN ORFNames=ebA6917;
OS Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)).
OC Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC Rhodocyclaceae; Aromatoleum.
OX NCBI_TaxID=76114;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EbN1;
RX PubMed=15551059; DOI=10.1007/s00203-004-0742-9;
RA Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F.,
RA Reinhardt R.;
RT "The genome sequence of an anaerobic aromatic-degrading denitrifying
RT bacterium, strain EbN1.";
RL Arch. Microbiol. 183:27-36(2005).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR555306; CAI10067.1; -; Genomic_DNA.
DR RefSeq; WP_011239712.1; NC_006513.1.
DR AlphaFoldDB; Q5NXZ7; -.
DR SMR; Q5NXZ7; -.
DR STRING; 76114.ebA6917; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAI10067; CAI10067; ebA6917.
DR KEGG; eba:ebA6917; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_4; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000006552; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..494
FT /note="Glycogen synthase"
FT /id="PRO_0000230234"
FT BINDING 24
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 494 AA; 52926 MW; 92EDE23A441210BF CRC64;
MNATRKAARL RVLFATPECA PWAKTGGLGD VSASLPAALA ALGLDVCVLL PGYPSVRQAA
RNARKVADIR SAHGLPSARL LRGRLPSGVP ALVLDCPSLY RREGGPYQDG EGVDYTDNAL
RFGLLSHVAA RLASAASPLV WRADILHCND WPTALAPAYL KLGLPGAAPS LIVVHNLAFQ
GIFPLDVAER LGLPPESLKS EGVEYWGKLS FLKAGLYYAD RIVAVSPTYA REIRTEAHGC
GMQGLLETRA NRLAGILNGI DMDAWNPRTD PHLDTNYDAD TLEDKAPNKR ALQAELGLAA
DDDALLLGMV TRLTDQKGID LVLDALPELL ARPVQLALLG GGDARFEQAW RQRAAARPDR
IAAVIGFDER LAHRIEAGAD AFVMPSRFEP CGLNQMYSQR YGTPPIVRAT GGLVDSVGDF
SVDGLHRGEA SGFLFAEATP AALVEAVDRA LKVFADRVAW RTLCCNGMAR DFSWGGSAGR
YARLYVAMRA AAAA
