GLGA_CHLAB
ID GLGA_CHLAB Reviewed; 475 AA.
AC Q5L562;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=CAB790;
OS Chlamydia abortus (strain DSM 27085 / S26/3) (Chlamydophila abortus).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=218497;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27085 / S26/3;
RX PubMed=15837807; DOI=10.1101/gr.3684805;
RA Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D.,
RA Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D.,
RA Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A.,
RA Price C., Barrell B.G., Parkhill J., Longbottom D.;
RT "The Chlamydophila abortus genome sequence reveals an array of variable
RT proteins that contribute to interspecies variation.";
RL Genome Res. 15:629-640(2005).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CR848038; CAH64232.1; -; Genomic_DNA.
DR RefSeq; WP_006344396.1; NC_004552.2.
DR AlphaFoldDB; Q5L562; -.
DR SMR; Q5L562; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAH64232; CAH64232; CAB790.
DR KEGG; cab:CAB790; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_5_0; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001012; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..475
FT /note="Glycogen synthase"
FT /id="PRO_0000230237"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 475 AA; 53182 MW; ABAFD4E9BF47B1BC CRC64;
MKIIQASVEC APFIKAGGLG DVVYSLSKAL SIHHDVEILL PFYPLLFPAF SSQVLDEHVF
AYNFLGRQNA TATSYRYEGM TLTVITLDSQ LELFSTSTIY TEDDTLRFSA FSAAAAAYIQ
KLDKVDVVHM HDWHVGLLAG LLKEPHLPSY PKRIFTIHNF SYRGYCSTQL LGASEISDFG
LSNYQLFRDP STSVLLKGAL YCSDYITTVS PSYAQDILND YSDYEIHDAI MSRRHVFCGI
LNGIDENIWN PETDPALAVR YGTHLLKSPD VLFTKKEENK IALYEKLGLS LEYSPLMCVI
SRIVEQKGPE FMKAAILHAM ENSYALVIAG TCYDQETQRQ FTNLQESLTT SPNIRIILDY
NDPLVRLIYG AADMICIPSH FEPCGLTQLI GMRYGTVPLV RSTGGLADTV AAGVNGFTFS
HTDNFNDFFH MLSQAVSTYR HEPDVWFQLV EEGMLRPSGL TTMAAHYLGV YNSLL
