GLGA_CHLPD
ID GLGA_CHLPD Reviewed; 489 AA.
AC A1BIY8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=Cpha266_2377;
OS Chlorobium phaeobacteroides (strain DSM 266).
OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC Chlorobium/Pelodictyon group; Chlorobium.
OX NCBI_TaxID=290317;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 266;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.,
RA Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T.,
RA Overmann J., Bryant D.A., Richardson P.;
RT "Complete sequence of Chlorobium phaeobacteroides DSM 266.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000492; ABL66365.1; -; Genomic_DNA.
DR RefSeq; WP_011746150.1; NC_008639.1.
DR AlphaFoldDB; A1BIY8; -.
DR SMR; A1BIY8; -.
DR STRING; 290317.Cpha266_2377; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABL66365; ABL66365; Cpha266_2377.
DR KEGG; cph:Cpha266_2377; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_0_10; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000008701; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..489
FT /note="Glycogen synthase"
FT /id="PRO_1000014345"
FT BINDING 20
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 489 AA; 55942 MW; 2180E27C0173AA23 CRC64;
MARRNFKVLY VSGEVSPFVR FSALADFMAS FPQAVEEEGF EARIMMPKYG TINDRKFRLH
DVLRLSDIEV HLKEKTDLLH VKVTALPSSK IQTYFLYNEK YFKRNGLFTD MHSGNDTKVN
TEKIIFFNVG VLETLQRLGW KPDIIHCHDW HASLIPLLLR TVYASNEFFK DIKTVLTIHN
IYRQGILPFK IFQKLLPEEV CSGLHRQNDE VNMLYTGVEH VDLLTTTSKQ YADTIRLDGE
ETYGLGRILE ERKENLHGIL NGIDTRQWNP ATDKLIKKRY SIERLDGKAD NKKALQEEAG
LSVDAERPLV GVIAGFDEFQ GADLLARSLE KLVALDMQLV ICGSGDKVYE KTFRDFAEQY
PEQVSLQIEY TDAFMHLAIA GMDILLMPGR IESCGMMQLF AMSYGTIPVV YAGGGIIETI
HELQEGIGSG FIFHEYTDDS LVGKLSEALA MYSDEERWPQ LVHEAMSKDF AWKSSAEEYD
QLYRQLLEP
