ID   GLGA_CHLTR              Reviewed;         474 AA.
AC   O84804;
DT   16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=CT_798;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AE001273; AAC68393.1; -; Genomic_DNA.
DR   PIR; D71469; D71469.
DR   RefSeq; NP_220318.1; NC_000117.1.
DR   RefSeq; WP_009872180.1; NC_000117.1.
DR   AlphaFoldDB; O84804; -.
DR   SMR; O84804; -.
DR   STRING; 813.O172_04445; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; AAC68393; AAC68393; CT_798.
DR   GeneID; 884597; -.
DR   KEGG; ctr:CT_798; -.
DR   PATRIC; fig|272561.5.peg.878; -.
DR   HOGENOM; CLU_009583_18_3_0; -.
DR   InParanoid; O84804; -.
DR   OMA; TWCPWYM; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..474
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188606"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   474 AA;  53370 MW;  3E3D1FCFB3029A73 CRC64;
     MKIIHTAIEF APVIKAGGLG DALYGLAKAL AANHTTEVVI PLYPKLFTLP KEQDLCSIQK
     LSYFFAGEQE ATAFSYFYEG IKVTLFKLDT QPELFENAET IYTSDDAFRF CAFSAAAASY
     IQKEGANIVH LHDWHTGLVA GLLKQQPCSQ LQKIVLTLHN FGYRGYTTRE ILEASSLNEF
     YISQYQLFRD PQTCVLLKGA LYCSDFVTTV SPTYAKEILE DYSDYEIHDA ITARQHHLRG
     ILNGIDTTIW GPETDPNLAK NYTKELFETP SIFFEAKAEN KKALYERLGL SLEHSPCVCI
     ISRIAEQKGP HFMKQAILHA LENAYTLIII GTCYGNQLHE EFANLQESLA NSPDVRILLT
     YSDVLARQIF AAADMICIPS MFEPCGLTQM IGMRYGTVPL VRATGGLADT VANGINGFSF
     FNPHDFYEFR NMLSEAVTTY RTNHDKWQHI VRACLDFSSD LETAANKYLE IYKQ