GLGA_DESAL
ID GLGA_DESAL Reviewed; 483 AA.
AC B8FBH4;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Dalk_2928;
OS Desulfatibacillum aliphaticivorans.
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulfatibacillum.
OX NCBI_TaxID=218208;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK-01;
RX PubMed=21651686; DOI=10.1111/j.1462-2920.2011.02516.x;
RA Callaghan A.V., Morris B.E., Pereira I.A., McInerney M.J., Austin R.N.,
RA Groves J.T., Kukor J.J., Suflita J.M., Young L.Y., Zylstra G.J., Wawrik B.;
RT "The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint
RT for anaerobic alkane oxidation.";
RL Environ. Microbiol. 14:101-113(2012).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001322; ACL04618.1; -; Genomic_DNA.
DR RefSeq; WP_015947687.1; NC_011768.1.
DR AlphaFoldDB; B8FBH4; -.
DR SMR; B8FBH4; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACL04618; ACL04618; Dalk_2928.
DR KEGG; dal:Dalk_2928; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_5_7; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000000739; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..483
FT /note="Glycogen synthase"
FT /id="PRO_1000126063"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 483 AA; 52582 MW; 108CFD47D81997A4 CRC64;
MKVLIVSSEL SPIAKEGGLG DAMAGLAPAL DALGCEVKVA IPGYGHVLES CPGAELITEN
VRVSMGYFNM TADLRKVEPA PGVEAYMVCN ESLFGRHGVY GDNDGLFMDN HKRYIFFSKS
IPALCSASRY IPDVILANDW QTGLIPALMD QGHMPQTASV FVIHNIGYLG YVPPEDASML
GLSNTYLSYE GMEFYGQLSL LKAGIAYANK LVTVSPTYSR EIQTTEQGAG LDGLMRKRSQ
DLAGILNGVD FQVWSPETDK HIPCNYSTAD MAGKGKCKKA LLDEMGMDSQ LMNAPVAGMV
TRLFSQKGIE LVIGAVPEIV ENGMGFILLG NGEESYVRDL RRLAQAYPGR FRFEEAFNEP
LAHRIMAGAD MLCVPSLYEP CGLTQMYALQ YGTIPVARAT GGLADTVRDI KAFAGKGNGF
TFDAFSPGAF ANAMDRAGRH YKNRKAWSAL RTKAMASAGV FTWDMAAEQY YSIFERAVRA
RRL
