GLGA_DESAP
ID GLGA_DESAP Reviewed; 500 AA.
AC B1I4F5;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Daud_1322;
OS Desulforudis audaxviator (strain MP104C).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Peptococcaceae;
OC Candidatus Desulforudis.
OX NCBI_TaxID=477974;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP104C;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Bruce D., Pitluck S., Lowry S.R., Larimer F., Land M.L.,
RA Hauser L., Kyrpides N., Ivanova N.N., Richardson P.;
RT "Complete sequence of chromosome of Desulforudis audaxviator MP104C.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000860; ACA59832.1; -; Genomic_DNA.
DR RefSeq; WP_012302417.1; NC_010424.1.
DR AlphaFoldDB; B1I4F5; -.
DR SMR; B1I4F5; -.
DR STRING; 477974.Daud_1322; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR PRIDE; B1I4F5; -.
DR EnsemblBacteria; ACA59832; ACA59832; Daud_1322.
DR KEGG; dau:Daud_1322; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_5_9; -.
DR OMA; MPSRWEP; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000008544; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..500
FT /note="Glycogen synthase"
FT /id="PRO_1000206426"
FT BINDING 20
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 500 AA; 57814 MW; A74192696BAD2F1C CRC64;
MFDRPLKILF VSSEVVPFAK TGGLADVAGS LPKALATVVD HGLSHHDVRV AMPRYKMIED
ARYVTDFPVW FADKNHEAII RQREIEAQFQ GARHTVPVYM IDNYQYYYRD GIYVFDDEAE
RFGFFCKAVL EMLPRLGWQP DVIHCNDWQC GPIPLFLKTH YRGDPFFSRM ATVFTIHNLQ
YQGNFPKEVL HMLGLGKEYF RPEALEFYGS VSFMKAGIQY ADVLTTVSRT YAREIQTPEY
GQRMEGVLRQ RAHELYGIVN GINYHEFDPK TDPRLHRNYD VDHWEHKKEN KFTLQREMNL
PVRDVPVLGL ITRLVDQKGL DLIAEIIDEL MRLDIQMVIL GKGDKYYEDM FREMKVQHPG
KIAAHIGFNV VLAQRIYAGS DMFLMPSRFE PCGLGQLISL RYGTIPIVRE TGGLADTVNE
YDLATGGGNG FVFKEYDARA LYSAIARALK LYREDQEAWG RLVRNAMEMD FSWARSAVEY
LQVYRDAMEK VSEERGIRIA
