GLGA_DESVM
ID GLGA_DESVM Reviewed; 488 AA.
AC B8DL94;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=DvMF_0841;
OS Desulfovibrio vulgaris (strain DSM 19637 / Miyazaki F).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfovibrio.
OX NCBI_TaxID=883;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19637 / Miyazaki F;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hazen T.C.,
RA Richardson P.;
RT "Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001197; ACL07797.1; -; Genomic_DNA.
DR RefSeq; WP_012611989.1; NC_011769.1.
DR AlphaFoldDB; B8DL94; -.
DR SMR; B8DL94; -.
DR STRING; 883.DvMF_0841; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACL07797; ACL07797; DvMF_0841.
DR KEGG; dvm:DvMF_0841; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_5_7; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..488
FT /note="Glycogen synthase"
FT /id="PRO_1000126064"
FT BINDING 17
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 488 AA; 55100 MW; B333FEDEA852F783 CRC64;
MRREVVFVTS EMYPFSKSGG LGDVLGAQPL ALHRMGVPTS VITPFYGRLR TADYGIHLTV
SDCHVGYPWD PITCDIYEAD YHGMKVYFVH RGEYFDRRYY YNDHKGDYFD NCERFIFFCR
AAMALLRRLG TPPAVLHAND WQSGLVPAYL HFWRQTDPFW ADTRSVMTIH NLAFQGRFAS
RLFTGCGLPP QAWTMSGVEF WGDFNLLKAG IAYADMVTTV SPSYAREILG PAYGCGLEGI
LQVRQHALHG ILNGADYGIW NPAQDKFLPC RYGPDDPQGF AGKQRCKAAL LDELGLAPEL
AHRPVLGFIG RLRGQKGIDL LLDIVPRLME RNVGVIILGE GNLAHEARAL DLMETYRGRL
CAIVGYTEDL AHRIQAGSDI FLMPSRYEPC GLTQMYALRY GTPPVATAVG GLRDTIVPWP
SPEATGFTFG RSDPQLFLEA ILDAVHYWEH DTEGWRAMMT RAMHQDFSWE RAGRSYLNLY
RQLGFDFS
