GLGA_DESVV
ID GLGA_DESVV Reviewed; 489 AA.
AC A1VC53;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Dvul_0998;
OS Desulfovibrio vulgaris subsp. vulgaris (strain DP4).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfovibrio.
OX NCBI_TaxID=391774;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DP4;
RX PubMed=19737303; DOI=10.1111/j.1462-2920.2009.01946.x;
RA Walker C.B., Stolyar S., Chivian D., Pinel N., Gabster J.A., Dehal P.S.,
RA He Z., Yang Z.K., Yen H.C., Zhou J., Wall J.D., Hazen T.C., Arkin A.P.,
RA Stahl D.A.;
RT "Contribution of mobile genetic elements to Desulfovibrio vulgaris genome
RT plasticity.";
RL Environ. Microbiol. 11:2244-2252(2009).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000527; ABM28019.1; -; Genomic_DNA.
DR RefSeq; WP_011791977.1; NC_008751.1.
DR AlphaFoldDB; A1VC53; -.
DR SMR; A1VC53; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABM28019; ABM28019; Dvul_0998.
DR KEGG; dvl:Dvul_0998; -.
DR HOGENOM; CLU_009583_18_5_7; -.
DR OMA; TWCPWYM; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000009173; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..489
FT /note="Glycogen synthase"
FT /id="PRO_1000014350"
FT BINDING 17
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 489 AA; 54634 MW; 9A5017F89C7F88CD CRC64;
MQRQVVFATS EMYPFSKSGG LGDVLGALPL ALHRMGVPTA VVTPFYGRLR TADYPIRLTV
SDCHVGYPWA PITCDVFEAD YHGMPVYFIH RGEYFDRRYY YNDHKGDYFD NCERFVFFCR
ALLALMRRLG QPPAVLHAHD WQTALVPAFL YFLRQGDPFW QDTRSVLTIH NLAFQGRFAS
RLFETSGLPP QAWSVDGAEF WGDFNLLKAG IAYADKVTTV SPSYAREILG PAYGSGLDGI
LRKRAHALHG ILNGADYDIW SPGNDRFLPC RYTPTDLAGK AQCKRALIEE LGLDPHLARR
PILGFIGRLR GQKGIDLLLD ILPRLMESDV GVIILGEGNL THEARALELM EAYRGRVCTI
VSYTEDLAHR IQAGSDIFLM PSRYEPCGLT QMYALRYGTP PVATAVGGLR DTIVPWPSPE
STGFTFGRCE SAAFLRAILD AVHLWTTAPG DWQGMVRRAM AQAFTWERAG RAYLDLYAQL
GVSPGEEGA
