GLGA_ELUMP
ID GLGA_ELUMP Reviewed; 482 AA.
AC B2KE25;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Emin_1221;
OS Elusimicrobium minutum (strain Pei191).
OC Bacteria; Elusimicrobia; Elusimicrobia; Elusimicrobiales;
OC Elusimicrobiaceae; Elusimicrobium.
OX NCBI_TaxID=445932;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pei191;
RX PubMed=19270133; DOI=10.1128/aem.02698-08;
RA Herlemann D.P.R., Geissinger O., Ikeda-Ohtsubo W., Kunin V., Sun H.,
RA Lapidus A., Hugenholtz P., Brune A.;
RT "Genomic analysis of 'Elusimicrobium minutum,' the first cultivated
RT representative of the phylum 'Elusimicrobia' (formerly termite group 1).";
RL Appl. Environ. Microbiol. 75:2841-2849(2009).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001055; ACC98771.1; -; Genomic_DNA.
DR RefSeq; WP_012415386.1; NC_010644.1.
DR AlphaFoldDB; B2KE25; -.
DR SMR; B2KE25; -.
DR STRING; 445932.Emin_1221; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACC98771; ACC98771; Emin_1221.
DR KEGG; emi:Emin_1221; -.
DR HOGENOM; CLU_009583_18_2_0; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001029; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..482
FT /note="Glycogen synthase"
FT /id="PRO_1000126073"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 482 AA; 54518 MW; 4B3A03A55FB69CC5 CRC64;
MNIVLAASEA FPFCKTGGLA DVTGSLAKEL SKHKGNRVIL FLPHYRNINR VASLKVVPGT
FLIPIGDRLE TASLSYISWG NVLVFFINNT KYFDRPELYR TAAGDYFDND ERFIFFNRAV
LESCKFIGYR PDIIHAHDWQ AGLLPAYLKT VYKTDAFFTR TRSLFTIHNM AYQGQYPYST
FIKTGFHTVD YVPERFEYYG GISYLKSGIV YADYVNTVSP NYAKEITLDE KMGFGMEGLL
RSRQDTFCGI LNGLDTGVWD PEHDPLIPYS YESFSPVKGK AACKQFLQNM LGLEVSPSKP
LVGIVSRMDY QKGLDLIPGV VNKYKDKVQF VVVGTGDSGM EKAFMALAKN NVGKVAYVAK
VDEELAHRVY AGSDIFLMPS RFEPCGLSQM ISMRYGTVPI VSRVGGLLDT VKGYDGITKY
ATGFFILEFS ETGIERSLDY ALKYYQDKRC WGMLIKNGME KDFSWTKSAQ EYQDLYKKII
SK
