GLGA_ERWT9
ID GLGA_ERWT9 Reviewed; 477 AA.
AC B2VJU7;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=ETA_32460;
OS Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB
OS 4357 / Et1/99).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=465817;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99;
RX PubMed=18462403; DOI=10.1111/j.1462-2920.2008.01639.x;
RA Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R.,
RA Geider K.;
RT "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic
RT bacterium in the genus Erwinia.";
RL Environ. Microbiol. 10:2211-2222(2008).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CU468135; CAO98292.1; -; Genomic_DNA.
DR RefSeq; WP_012442919.1; NC_010694.1.
DR AlphaFoldDB; B2VJU7; -.
DR SMR; B2VJU7; -.
DR STRING; 465817.ETA_32460; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAO98292; CAO98292; ETA_32460.
DR KEGG; eta:ETA_32460; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_6; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001726; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..477
FT /note="Glycogen synthase"
FT /id="PRO_1000126074"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 477 AA; 52719 MW; E19A04BD0779A225 CRC64;
MQVLHVCSEL FPLLKTGGLA DVVGALPAAQ IAAGDDTRVL LPAFPDLKKG ITQIQVVAQL
QTFAGYVELH FGHFNGVGIY LIDAPGLYDR PGSPYHDESQ YAYSDNYLRF ALLGWVSCEL
ACGLDPWWRP EVVHAHDWHA GLSCAYLAAR GRPAKSVFTV HNLAYQGLFN ARHMEQIQLP
HSFFDVYGME FHGQISYLKA GLFYADHVTA VSPTYAREIT QPEFGYGMEG LLKQRLLEGR
LSGILNGVDP AIWNPAHDLL LAARYNRDVL DAKRENKRQL QIAMGLKIDE KAPIFAVVSR
LTKQKGLDLV LEALPGLLEQ GGQLVVLGAG DAELQQGFLA AAAENPGQVG VQIGYHEAFS
HRIMGGADVI LVPSRFEPCG LTQLYALKYG TLPLVRRTGG LADTVNDCSL ENLADGIASG
FSFEDSNAWS LLRAIRRSFV LWSRPSLWRY VQRQAMGMDF SWQVAAVAYR DLYQRLL
