ID   GLGA_GLOVI              Reviewed;         458 AA.
AC   Q7NM37;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=glr0932;
OS   Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC   Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae;
OC   Gloeobacter.
OX   NCBI_TaxID=251221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29082 / PCC 7421;
RX   PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA   Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA   Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA   Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT   cyanobacterium that lacks thylakoids.";
RL   DNA Res. 10:137-145(2003).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; BA000045; BAC88873.1; -; Genomic_DNA.
DR   RefSeq; NP_923878.1; NC_005125.1.
DR   RefSeq; WP_011140934.1; NC_005125.1.
DR   AlphaFoldDB; Q7NM37; -.
DR   SMR; Q7NM37; -.
DR   STRING; 251221.35211495; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; BAC88873; BAC88873; BAC88873.
DR   KEGG; gvi:glr0932; -.
DR   PATRIC; fig|251221.4.peg.951; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_3; -.
DR   InParanoid; Q7NM37; -.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   PhylomeDB; Q7NM37; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000557; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..458
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188619"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   458 AA;  51534 MW;  E011CF4C1D087517 CRC64;
     MKVLFAAAEC APLAKVGGMA DVVGSLPLAL AEMGLDVRII LPYYGFLGEL PKSEQPVWTG
     GAMFQQVEIY EARLPGSDIP LYLVGHPAFA NERIYGFEDE AWRFTLFSRT VAEFLWRGGW
     DPQVLHCHDW HTGLLPLWMR SMPVMTVFTI HNLAYQGPPL PYFRAFVDVP YDTGAWNPMV
     AGIIHSDAIT AVSPTYAREI CTPEYGERLD GLLRGQGNRL TGILNGINTK ALDPATDKHL
     TVNYDTTSLD RRVENKLALQ REFGFEVSAD RLLVGIVSRL VDQKGFDLLA PLWDNWMHTS
     GAQLVVLGSG DPFYEFLFRS AAERYPDRIK AVLSYNVPIA QRIYGGADLF LMPSRFEPCG
     IGQMIALRYG AVPLVRKTGG LADTVFFHNP LDEKGNGFLF DRYDPANLLA MLYRAEEAFR
     YKDYWRRLQL RGMEADLSWR ASAHQYADLY KSLIARLG