ID   GLGA_KLEP7              Reviewed;         477 AA.
AC   A6TF48;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN   OrderedLocusNames=KPN78578_37580; ORFNames=KPN_03795;
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578;
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; CP000647; ABR79182.1; -; Genomic_DNA.
DR   RefSeq; WP_002920564.1; NC_009648.1.
DR   AlphaFoldDB; A6TF48; -.
DR   SMR; A6TF48; -.
DR   STRING; 272620.KPN_03795; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   PRIDE; A6TF48; -.
DR   EnsemblBacteria; ABR79182; ABR79182; KPN_03795.
DR   KEGG; kpn:KPN_03795; -.
DR   HOGENOM; CLU_009583_18_2_6; -.
DR   OMA; TWCPWYM; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..477
FT                   /note="Glycogen synthase"
FT                   /id="PRO_1000014366"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   477 AA;  53005 MW;  D5C107EFCD42CC3A CRC64;
     MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IAEGIDTRVL LPAFPDIRRG VVDAQVVTRR
     DTFAGRITLL YGHFNGVGIY LIDAPHLYDR PGSPYHDTNQ HAYPDNVLRF ALLGWVGSEM
     ASGLDPFWRP DVVHAHDWHA GLTPAYLAAR GRPAKSVFTV HNLAYQGMFY SWHMNDIELP
     WSFYNMHGLE FNGQISFLKA GLYYADHITA VSPTYAREIT EPQYAYGMEG LLRQRHHEGR
     LSGILNGVDD GIWSPQNDLL LPMRYDRDTL EEKAENKRQL QIAMGLKVDD KAPLFAVVSR
     LTSQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEHPGKVG VQIGYHEAFS
     HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG LADTVADSSL ENLADGLATG
     FVFEDSNALS LLRAIRRAFV LWSRPSLWRY VQRQAMNMDF SWQVAANSYR ELYQRLM