GLGA_MARMS
ID GLGA_MARMS Reviewed; 476 AA.
AC A6VUP1;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Mmwyl1_1241;
OS Marinomonas sp. (strain MWYL1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=400668;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MWYL1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y.,
RA Richardson P.;
RT "Complete sequence of Marinomonas sp. MWYL1.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000749; ABR70170.1; -; Genomic_DNA.
DR RefSeq; WP_012068955.1; NC_009654.1.
DR AlphaFoldDB; A6VUP1; -.
DR SMR; A6VUP1; -.
DR STRING; 400668.Mmwyl1_1241; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABR70170; ABR70170; Mmwyl1_1241.
DR KEGG; mmw:Mmwyl1_1241; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_6; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..476
FT /note="Glycogen synthase"
FT /id="PRO_1000081327"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 476 AA; 53278 MW; F792B4483BC56776 CRC64;
MKILFAASEI YPLIKTGGLA DVAGALPVAL RKKGHDVKLI MPAYQGILEK VAPIQKSINL
GNPFGVGDLL LLETHIPEND TPIWLLQCQA LYEREDGPYV DKNGIDFEDN HIRFAALSWA
TATLALHGHL MNWQADILHL NDWQTGFAAA YLESWKVEHI PVVTTVHNLR YNGSFDMNQF
SAMHLSPELL NMHGMEFYGR FSGLKAGLVY ANAVTTVSPT YAKEILTPEY GDGLDGALRA
MQDRLVGILN GVDYNQWSPE KDTLIPHNYD IDTLSQKQAN KLALLQENGL SEDLNQPVFG
VVSRLTEQKG LDLVLQVMPA LLEKGARLVV LGSGDKYLES QYLELQNNYP NQVSVRIGYF
EDYSHRLQAG IDALLIPSRF EPCGLTQLYA LKYGTLPIVR QTGGLADTVF EDGERANGFV
FKEASAKALQ AAMERSIECF HDTNRWQEKQ KNAMCYDYSW DAVTDQWISL YESLIN
