GLGA_MARN8
ID GLGA_MARN8 Reviewed; 488 AA.
AC A1U0K2;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Maqu_1435;
OS Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter
OS aquaeolei).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Marinobacteraceae; Marinobacter.
OX NCBI_TaxID=351348;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700491 / DSM 11845 / VT8;
RX PubMed=21335390; DOI=10.1128/aem.01866-10;
RA Singer E., Webb E.A., Nelson W.C., Heidelberg J.F., Ivanova N., Pati A.,
RA Edwards K.J.;
RT "Genomic potential of Marinobacter aquaeolei, a biogeochemical
RT 'opportunitroph'.";
RL Appl. Environ. Microbiol. 77:2763-2771(2011).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000514; ABM18521.1; -; Genomic_DNA.
DR RefSeq; WP_011784923.1; NC_008740.1.
DR AlphaFoldDB; A1U0K2; -.
DR SMR; A1U0K2; -.
DR STRING; 351348.Maqu_1435; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABM18521; ABM18521; Maqu_1435.
DR KEGG; maq:Maqu_1435; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_6; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000000998; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..488
FT /note="Glycogen synthase"
FT /id="PRO_1000206432"
FT BINDING 16
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 488 AA; 54554 MW; 929B729314D2D32F CRC64;
MTRVLFATSE VFPLVKTGGL ADVSASLPEA LCRLGYDCQI LLPGYPAALK AAREAGSRRK
TRFRYGQYDV SLWQTRLPGT AVTLWLVDCP ALFDRAGDSP YQNEEGEDWW DNAHRFHLFG
RIGAMLALGQ LGLAWRPDIV HCNDWQSALI PVFLADSQDA PKTVFTIHNL AYQGLFSHET
FRALGLPDSL WRYEFLEFHG QLSFIKGGLV FSDAITTVSP SYADEIQTPW FGNGLDGLLR
HKSSRLHGIL NGIDTRQWNP EADPHLEFHY GADYPANKSQ CQARLQQELG LEVCGAPLLG
FVGRLVEQKG LDWLLGVIKP LLERGCQFAL LGSGEHHYQE SLKAMVREWP GQCSLTLGYN
EGLAHRITAG ADIFLMPSRF EPCGLNQMYS LRYGTVPVVH GVGGLNDTVF DPNEETPEQA
NGFVFREATP DALHAAITRA LAAREDRKTW RKLQENGMKG DYSWKNRAGE YAALYRNLIA
GNDRIHED
