GLGA_MYCMO
ID GLGA_MYCMO Reviewed; 476 AA.
AC Q6KHP2;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=MMOB4020;
OS Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711) (Mesomycoplasma
OS mobile).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mesomycoplasma.
OX NCBI_TaxID=267748;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43663 / 163K / NCTC 11711;
RX PubMed=15289470; DOI=10.1101/gr.2674004;
RA Jaffe J.D., Stange-Thomann N., Smith C., DeCaprio D., Fisher S., Butler J.,
RA Calvo S., Elkins T., FitzGerald M.G., Hafez N., Kodira C.D., Major J.,
RA Wang S., Wilkinson J., Nicol R., Nusbaum C., Birren B., Berg H.C.,
RA Church G.M.;
RT "The complete genome and proteome of Mycoplasma mobile.";
RL Genome Res. 14:1447-1461(2004).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; AE017308; AAT27888.1; -; Genomic_DNA.
DR RefSeq; WP_011264922.1; NC_006908.1.
DR AlphaFoldDB; Q6KHP2; -.
DR SMR; Q6KHP2; -.
DR STRING; 267748.MMOB4020; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR PRIDE; Q6KHP2; -.
DR EnsemblBacteria; AAT27888; AAT27888; MMOB4020.
DR KEGG; mmo:MMOB4020; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_14; -.
DR OMA; TWCPWYM; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000009072; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..476
FT /note="Glycogen synthase"
FT /id="PRO_0000188624"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 476 AA; 54749 MW; 8A4B2F5B8A223574 CRC64;
MKILYISVEC FPFIKTGGLG DVAYSFPKTL KKLGNDIKVF LIYSDSISEK YKEKMRSAYF
FSLDLNGKSF PVEIFSLVMD DIEYLFFNDP SFKNIERTAY LDLHENSTFY LIFNKAISKF
LELSAFKPEI IHANDWHTGI LPLFLSGEKN ENSKLKVVFT IHNLQYQGVF GASNVLKYLN
EKERSNSLLS EIISNDIFNF MKAGIISSDI VTTVSETYKE EIKQPMQGMG LESVLNKYNS
KLRGIINGLD YDIFNPSIDK YIEAKYDVSN YKEAKLINKI ALQKELNLEQ NKKIFLIGMI
SRLANQKGID LVLNSLWNIV KDNDIQFVVL GTGDVNYESN LKSFGNKYPR NFKFINKFSD
ELSHKLYAGL DAFLIPSLFE PCGLTQLISL KYGCIPIARA TGGLIDTITS YNDKQENANG
FLFKEYTPEA LYKSVKLAKN LFYNNKPEWN KLIYFGMDQR FGWEEIAKKY LESIYK
