GLGA_NITEC
ID GLGA_NITEC Reviewed; 502 AA.
AC Q0AIE6;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Neut_0608;
OS Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57).
OC Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=335283;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 101675 / C91 / Nm57;
RX PubMed=17991028; DOI=10.1111/j.1462-2920.2007.01409.x;
RA Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S.,
RA Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M., Wei X.;
RT "Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas
RT eutropha C91: implications for niche adaptation.";
RL Environ. Microbiol. 9:2993-3007(2007).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000450; ABI58880.1; -; Genomic_DNA.
DR RefSeq; WP_011633721.1; NC_008344.1.
DR AlphaFoldDB; Q0AIE6; -.
DR SMR; Q0AIE6; -.
DR STRING; 335283.Neut_0608; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABI58880; ABI58880; Neut_0608.
DR KEGG; net:Neut_0608; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_4; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001966; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..502
FT /note="Glycogen synthase"
FT /id="PRO_1000014370"
FT BINDING 24
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 502 AA; 54628 MW; E50CFA825922C727 CRC64;
MPSSSPRKNI RVLFVTPEVF PLCKTGGLGD VSAALPVALR ALKMDARLLL PGYPAVLAGL
KSRRKVATFD LQPHFPPATL LSSRLQINES VSVPLYVIHC PALYQRTGGI YLDDTGQDWP
DNAQRFGLLS KIGALLASDA SPLAWVPDIV HCNDWQSGLT PAYLHFHSGK KAASLITLHN
LAFQGNFPSD EVAKLGLPDE SFSMHGAEFY GNLSFLKAGI YYSDHISTVS PGYAREIQQE
PLGFGLQGLL AKRSDDITGI VNGIDTAIWN PATDPYLVKK YTSRNLSAKA ANKLALQQTM
GLENNQAIPL FGTVSRLTHQ KGSDIMLQVA PMLADLPAQL ALLGSGDALL EQQLAALAQA
FPTKIAVRIG YDEALSHLIN AGTDCFLMPS RFEPCGLNQM YSQHYGTPPV VHATGGLMDT
VVDLTPETLA DKSASGFHFH EMTADSFMEG IKRAINAYHN TRLWKNLQRN GMQKDFSWQA
SASAYQSIYS LLMQKNRPAS TA
