ID   GLGA_NITEU              Reviewed;         495 AA.
AC   Q82SP3;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=NE2264;
OS   Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS   14298).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=228410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298;
RX   PubMed=12700255; DOI=10.1128/jb.185.9.2759-2773.2003;
RA   Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L.,
RA   Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A.,
RA   Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.;
RT   "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT   chemolithoautotroph Nitrosomonas europaea.";
RL   J. Bacteriol. 185:2759-2773(2003).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AL954747; CAD86176.1; -; Genomic_DNA.
DR   RefSeq; WP_011112755.1; NC_004757.1.
DR   AlphaFoldDB; Q82SP3; -.
DR   SMR; Q82SP3; -.
DR   STRING; 228410.NE2264; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; CAD86176; CAD86176; NE2264.
DR   KEGG; neu:NE2264; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_4; -.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   PhylomeDB; Q82SP3; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000001416; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..495
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188625"
FT   BINDING         24
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   495 AA;  54721 MW;  A365FB891C2A685D CRC64;
     MSSSPSRKNP RVLFVTSEVF PLCKTGGLGD VSAALPAALR ELKADVRLLV PGYPSVLSGL
     KYKRKLAEFD LLPHFPPTTL FSSRLQINES VSLPLYVIHC PELYQRPGGI YLDDDGQDWP
     DNAQRFGLLS KMGALLASDA SPLSWIPDII HCNDWQSGLT PAYLHYHSGK KAASLMTLHN
     LAFQGCFPPD EVARLGLPPE SFSVHGVEYY GNLSFLKAGI YYATRITTVS PTYAREIQHE
     PLGFGLQGLL AERSNAITGI INGIDNTVWN PATDPHIVKK YSSRNLAAKK INKLALQREM
     GLEENETIPL FAGISRLSYQ KGYDILLQVA PMLADLPAQL VLLGKGDQSL EKQLVMLAQT
     NPARIAVRID YDEALSHRIN ASADCFLMPS RFEPCGLNQM YSQRYGTPPI VHTTGGLIDT
     VTDLAPDTPA GESASGFHFH EMTADAFMNG IGRAIDAYYN TRLWKTLQHN GMRKDFSWRS
     SALAYLSIYS LLMQR