ID   GLGA_OCEIH              Reviewed;         477 AA.
AC   Q8ET54;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=OB0409;
OS   Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS   3954 / HTE831).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=221109;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831;
RX   PubMed=12235376; DOI=10.1093/nar/gkf526;
RA   Takami H., Takaki Y., Uchiyama I.;
RT   "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT   and its unexpected adaptive capabilities to extreme environments.";
RL   Nucleic Acids Res. 30:3927-3935(2002).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; BA000028; BAC12365.1; -; Genomic_DNA.
DR   RefSeq; WP_011064815.1; NC_004193.1.
DR   AlphaFoldDB; Q8ET54; -.
DR   SMR; Q8ET54; -.
DR   STRING; 221109.22776088; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   PRIDE; Q8ET54; -.
DR   EnsemblBacteria; BAC12365; BAC12365; BAC12365.
DR   KEGG; oih:OB0409; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_9; -.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   PhylomeDB; Q8ET54; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000822; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..477
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188626"
FT   BINDING         16
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   477 AA;  55251 MW;  921CD2B33C9ACAE9 CRC64;
     MKNILFVTSE CTPFIKTGGL ADVSGSLPQA LQEHGGMEVR VMLPLYDEID RSWKDQFEFV
     CAFTVSLGWR EQTAELYRYR YNDVTYYFIG NDYYFTRKGI YGYYDDGERF VFFSQAIIAS
     LEYIDFIPSV LHAHDWQTGI AVALAKIYQP IEELITVFTI HNIYYQGTMP LTTFDDFFQL
     GREHLAGMEW NQMINSLKSG IFHADKITTV SPTYAEEILT PYYGAGLEEM LWNRREDLIG
     VLNGIDLKDY NPAIDKSLPV NYRSARSKKI ENRKLLYEEI GLNLKDGVPL YIMVTRLVEQ
     KGIHLVQRIL EEFLQEDIQL IVLGNGEQEF EYYFKDIEYR YPDKMITHLH FNESLARRLY
     ASADFLLMPS KFEPCGLSQL IALQYKTVPI VRETGGLKDT IIAFNEITGE GNGFRFANYN
     AHELLHVLKY SLEIYQQPSL WSVLIKNVNK SKFSWKDSAS AYADVYQQLD ASSVSYK