GLGA_PECCP
ID GLGA_PECCP Reviewed; 479 AA.
AC C6DH76;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=PC1_3934;
OS Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=561230;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC1;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Balakrishnan V., Glasner J., Perna N.T.;
RT "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001657; ACT14949.1; -; Genomic_DNA.
DR RefSeq; WP_015842030.1; NC_012917.1.
DR AlphaFoldDB; C6DH76; -.
DR SMR; C6DH76; -.
DR STRING; 561230.PC1_3934; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACT14949; ACT14949; PC1_3934.
DR KEGG; pct:PC1_3934; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_6; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000002736; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..479
FT /note="Glycogen synthase"
FT /id="PRO_1000206433"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 479 AA; 52813 MW; 0FA72413BCC0C637 CRC64;
MRVLHVCSEL FPLLKTGGLA DVAGALPGAQ IAAGMDVRVI LPAFPDLKKG IANLQVVREL
DTFAGHVTLL FGHFNGVGIY LIDVPELYER AGSPYHDPAL YAYADNYLRF ALLGWMGCEM
ACGLDHYWRP DIVHAHDWHA GLTCAYLAAR NRPAKSIFTV HNLAYQGLFD ARHMPDLHLP
REFFQVYGLE FYGQISYLKA GLYYADHITT VSPTYAHEIT LPAYGYGMEG LLKSREEEGR
LSGILNGVDE MIWNPAHDPL LASHYSRDTL ANKAENKRRL QTAMGLKVDD KVPVFAIVSR
LTSQKGLDIA LSAIPDLLEQ GGQVVVLGAG DADLQEGFLA AAAEYHGQVG VQIGYHEAFS
HRIIGGADVI MVPSRFEPCG LTQLYGLKYG TLPLVRRTGG LADTVSDCSL ENLADGLASG
FVFNDCSVGS LSRAIRRVFV LWSRPTLWRY VQRQAMAMDF GWQVAAQAYG ALYQRLYTH
