GLGA_PETMO
ID GLGA_PETMO Reviewed; 483 AA.
AC A9BG68;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Pmob_1105;
OS Petrotoga mobilis (strain DSM 10674 / SJ95).
OC Bacteria; Thermotogae; Petrotogales; Petrotogaceae; Petrotoga.
OX NCBI_TaxID=403833;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10674 / SJ95;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Noll K., Richardson P.;
RT "Complete sequence of Petroga mobilis SJ95.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000879; ABX31824.1; -; Genomic_DNA.
DR RefSeq; WP_012208925.1; NC_010003.1.
DR AlphaFoldDB; A9BG68; -.
DR SMR; A9BG68; -.
DR STRING; 403833.Pmob_1105; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABX31824; ABX31824; Pmob_1105.
DR KEGG; pmo:Pmob_1105; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_0; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000000789; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..483
FT /note="Glycogen synthase"
FT /id="PRO_1000081328"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 483 AA; 55456 MW; D6FF372FB376D5BC CRC64;
MKIAYVSYEV SPFAKAGGLA DVAGALPKYI KNAGEDIYVV MPFHKNIENN YDISKFEVVK
TGLIPDSHTH KSPFSVYKSY LEGSSVVIYF IKTDSLYDSK NIYDEENIFL KTSYFCDSAL
KTIKECEPDT NVININDWHT SLIPVYLKTH YLQDNILKKI ATILTIHNIG YQGLFNPEVL
NQAGLPNYLF NMNALEYYGK VNVLKGGILF SNIINTVSPT YAKEIQSEEY GYGLEGILKV
RSEDLFGILN GIDYSIYDPL KDPHIFHPIE SYEDKLKNKT SLQEYLGLTK DENITLISFI
GRLFEQKGID LISKIMDLLL LNDIQFVLLG TGDKKYEEYF VTLTKLYPKK ISINITFDVD
LAQKIYAGSD IFLMPSKYEP CGLGQMYSMR YGTVPVVRYT GGLKDTVSEY NPKDKKGTGF
GFHEYKEADL LYTLMKAIYF HQKRKDDWTN IFENCMKEDF SYEKTAKKYI ELYKIALDKK
RGY
