GLGA_PHOPR
ID GLGA_PHOPR Reviewed; 508 AA.
AC Q6LKA1;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=PBPRB0406;
OS Photobacterium profundum (strain SS9).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=298386;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1253 / SS9;
RX PubMed=15746425; DOI=10.1126/science.1103341;
RA Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA Bartlett D.H., Valle G.;
RT "Life at depth: Photobacterium profundum genome sequence and expression
RT analysis.";
RL Science 307:1459-1461(2005).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CR378676; CAG22279.1; -; Genomic_DNA.
DR RefSeq; WP_011220490.1; NC_006371.1.
DR AlphaFoldDB; Q6LKA1; -.
DR SMR; Q6LKA1; -.
DR STRING; 298386.PBPRB0406; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAG22279; CAG22279; PBPRB0406.
DR KEGG; ppr:PBPRB0406; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_6; -.
DR OMA; CGWVHGR; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000000593; Chromosome 2.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..508
FT /note="Glycogen synthase"
FT /id="PRO_0000230253"
FT BINDING 27
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 508 AA; 56993 MW; 89AEC27330E8AB90 CRC64;
MATKKTSLTK HPLKILFVSS EVEGFAKTGG LADVAKSLPA ALKKMGHDVR IVMPFYQTIN
GKDNAVAILS TELLVESQPF AVSYQVMQLD EGNVPVYALD APQYYDRPEL YAENNQAYAD
NGERFTFLSA ASLDLCEKLG FQPDVIHCND WHTGLIPFLL KTRYAESDFF AKSKSVITIH
NAVFKGVFNY DQYSLIPELI QRRYINAEMD PSHISMLKAG VAYADKVNAV SPNYASELLT
HLGSHGMEAD FQNRAKDLYG IINGCDYDDW NPETDVYIKQ KFKANKVSLA RGKKACRRDL
QKQVNLPEVD VPVYGMVCRL TEQKGLHYLI PVLEDFLLND VQVVIVGTGD PTLASALRDI
SEQHSDKFAF VETYSNPLAH CVEAGVDFFM MPSEFEPCGL NQMYSLAYGT LPIVRSVGGL
KDTVIDYDQT PQVATGFIYD TPTPEALLIK LQRSLLLYCQ RPQEFKRLQQ NAMACKFNWD
ESAEQYLDMY LGGEQSLVNE ICNDKVDA
