ID   GLGA_PROM3              Reviewed;         499 AA.
AC   A2CAW5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=P9303_18831;
OS   Prochlorococcus marinus (strain MIT 9303).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9303;
RX   PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA   Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA   Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA   Richardson P., Chisholm S.W.;
RT   "Patterns and implications of gene gain and loss in the evolution of
RT   Prochlorococcus.";
RL   PLoS Genet. 3:2515-2528(2007).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; CP000554; ABM78625.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2CAW5; -.
DR   SMR; A2CAW5; -.
DR   STRING; 59922.P9303_18831; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; ABM78625; ABM78625; P9303_18831.
DR   KEGG; pmf:P9303_18831; -.
DR   HOGENOM; CLU_009583_18_2_3; -.
DR   OMA; TWCPWYM; -.
DR   BioCyc; PMAR59922:G1G80-1633-MON; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000002274; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..499
FT                   /note="Glycogen synthase"
FT                   /id="PRO_1000014375"
FT   REGION          471..499
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   499 AA;  56436 MW;  9F4D5813E2099E59 CRC64;
     MRVLFAAAEC APMVKVGGMG DVVGSLPPAL AKLDHDVRLI MPGYGKLWSL LDIPTDPIWR
     GQTMGNEFAI YETSHPSNGL PLYLVGHPVF DPERIYGGED EDWRFTFFAS ATTEFAWNVW
     KPQVLHCHDW HTGMIPVWMH QDPEVSTVFT IHNLKYQGPW RWKLDRMTWC PWYMQGDHTM
     AAALLYADRV NAVSPTYARE ICTSEYGESL DGLLNYISGK LRGILNGIDL QDWDPANDKS
     LPATFSADDL SGRAVNKQAL QQRMGLEVNP DTYLLGMVSR LVDQKGVDLL LQVTERLLAY
     TDSQIVVLGT GERGLESSLW QLAIQNPGRF SVFLTYDDDL ARLIYGGSDA FLMPSRFEPC
     GISQLLAMRY GSVPVVRKVG GLVDTVPSYD PIHKTGTGFC FDRFEPVDFY TALVRSWEAF
     RHRDCWRELQ QRAMTQNYSW DRSALDYDQM YRDVCGLKEP SPDAAVVEQF SLGQGSDPSR
     QGQDSNAKKR TRRKKKGND